Gene Regulation, Epigenomics and Transcriptomics (GREAT)

*Asterisk indicates faculty who have taken mentor training and/or implicit bias training.

John Adams
John Adams
Vitamin D and steroid hormones
Patrick Allard*
Patrick Allard*
aims to dissect the genetic and epigenetic pathways that connect environmental cues to health effects across the lifespan and across generations
Valerie A. Arboleda*
Valerie A. Arboleda*
Epigenetics, Genomics, Rare Disease, Computational Medicine
Aparna Bhaduri*
Aparna Bhaduri*
human brain development, as well as how these trajectories are hijacked in brain cancer such as glioblastoma
Douglas  Black*
Douglas Black*
Regulation of gene expression through pre-mRNA splicing
Paul Boutros*
Paul Boutros*
create biomarkers to maximize cure and minimize morbidities
Michael Carey
Michael Carey
Mechanisms of eukaryotic gene transcription
Guillaume Chanfreau*
Guillaume Chanfreau*
RNA Processing, Degradation and Quality Control
Genhong Cheng
Genhong Cheng
Host immune responses to infections, cancers and metabolic challenges
Hilary Coller*
Hilary Coller*
Molecular basis of cellular quiescence
Luis De La Torre-Ubieta
Luis De La Torre-Ubieta
Mechanisms of gene regulation in neocortical development and neuropsychiatric disease
Jason Ernst*
Jason Ernst*
Machine learning methods to analyze high-throughput data
Oliver Fregoso*
Oliver Fregoso*
Molecular and evolutionary approaches to understand virus-host interactions of HIV
Robert  Goldberg
Robert Goldberg
Gene regulatory networks required for seed development
Feng Guo*
Feng Guo*
RNA-targeting drug development
Oliver Hankinson
Oliver Hankinson
Carcinogenesis, chemoprevention and hypoxia
Alexander Hoffmann*
Alexander Hoffmann*
Systems biology approaches to understand immune responses
Steven Jacobsen
Steven Jacobsen
Mechanisms of epigenetic gene regulation by DNA methylation
Tracy Johnson*
Tracy Johnson*
Pre-messenger RNA splicing and processing; chromatin modification
Siavash Kurdistani*
Siavash Kurdistani*
Epigenetics in biology and disease
Chentao Lin
Chentao Lin
Signal Transduction of plant photoreceptors 
Jeffrey Long
Jeffrey Long
Chromatin modifiers regulating plant stem cells
Bill Lowry
Bill Lowry
Cell fate decisions in development and cancer
Chongyuan Luo*
Chongyuan Luo*
Genetic basis of neurodevelopmental disorders
Hanna Mikkola*
Hanna Mikkola*
Molecular regulation of hematopoietic stem cell development
Jeffery F. Miller*
Jeffery F. Miller*
Mechanisms of bacterial pathogenesis and immunity
Lachezar Nikolov*
Lachezar Nikolov*
Genetic and developmental basis of plant secretory structures, single-cell transcriptomics and gene regulatory networks driving floral development
Bennett Novitch*
Bennett Novitch*
Mechanisms of differentiation of neural stem cells into defined lineages
Kathrin Plath*
Kathrin Plath*
Epigenetic regulation of stem cell self-renewal, differentiation, and cancer
Dinesh Rao*
Dinesh Rao*
Physiology and pathology of non-coding RNA in hematopoiesis
Tamer Sallam*
Tamer Sallam*
Contributions of long non-coding RNAs in cardiometabolic disease
Stephen Smale*
Stephen Smale*
Gene regulation mechanisms controlling inflammatory responses
Elizabeth Tarling
Elizabeth Tarling
investigate how protein aggregation affects cancer development and progression in order to identify novel therapeutic targets and develop peptide drugs with anti-cancer capabilities
Peter Tontonoz
Peter Tontonoz
Regulation of gene expression by nuclear hormone receptors
Thomas Vallim*
Thomas Vallim*
Transcriptional and post-transcriptional regulation of lipid metabolism
Claudio Villanueva*
Claudio Villanueva*
molecular mechanisms that underly the cellular plasticity of adipocytes
Thomas Vondriska*
Thomas Vondriska*
Epigenomic regulation of the cardiovascular system
Cun-Yu Wang
Cun-Yu Wang
Molecular regulation of dental stem cell property
Joanne Weidhaas*
Joanne Weidhaas*
impact of microRNAs and germline mutations that disrupt their function on oncogenesis as well as the stress response to all types of cancer therapies, including radiation and immune therapy
James Wohlschlegel
James Wohlschlegel
Dissecting Ubiquitin-regulated Signaling Networks
Xinshu Grace Xiao*
Xinshu Grace Xiao*
Genomics and bioinformatics of post-transcriptional gene regulation in biology & disease
Xian-Jie Yang
Xian-Jie Yang
Development of the vertebrate central nervous system
Jesse Zamudio*
Jesse Zamudio*
Functional RNAs in Human Development and Disease
Xianghong (Jasmine) Zhou
Xianghong (Jasmine) Zhou
developing computational and experimental methods on non-invasive cancer diagnosis and monitoring using circulating free DNA (cfDNA) and other materials released by tumor in blood