Jie Zheng*

Email: jzheng@jsei.ucla.edu

Publications:

Bonnet C, Han CS, Deng SX, Zheng JJ. Positive cooperativity in synergistic activation of Wnt proteins. Mol Biol Rep. 2024 Aug 18; 51(1):914. view on PubMed

Bonnet C, González S, Deng SX, Zheng JJ. Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. Sci Rep. 2023 09 21; 13(1):15670. view on PubMed

Graybeal K, Sanchez L, Zhang C, Stiles L, Zheng JJ. Characterizing the metabolic profile of dexamethasone treated human trabecular meshwork cells. Exp Eye Res. 2022 01; 214:108888. view on PubMed

Zhang C, Mei H, Robertson SYT, Lee HJ, Deng SX, Zheng JJ. A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion. iScience. 2020 May 22; 23(5):101075. view on PubMed

Zhang C, Miller DJ, Guibao CD, Donato DM, Hanks SK, Zheng JJ. Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin. J Biol Chem. 2017 11 03; 292(44):18281-18289. view on PubMed

Ahadome SD, Zhang C, Tannous E, Shen J, Zheng JJ. Small-molecule inhibition of Wnt signaling abrogates dexamethasone-induced phenotype of primary human trabecular meshwork cells. Exp Cell Res. 2017 08 01; 357(1):116-123. view on PubMed

Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL. Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. J Biol Chem. 2017 04 07; 292(14):5898-5908. view on PubMed

Bao J, Marathe B, Govorkova EA, Zheng JJ. Drug Repurposing Identifies Inhibitors of Oseltamivir-Resistant Influenza Viruses. Angew Chem Int Ed Engl. 2016 Mar 01; 55(10):3438-41. view on PubMed

Lee HJ, Bao J, Miller A, Zhang C, Wu J, Baday YC, Guibao C, Li L, Wu D, Zheng JJ. Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. J Biol Chem. 2015 Dec 18; 290(51):30596-606. view on PubMed