Quen Cheng*

Publications:

Chavez C, Lin K, Malveaux A, Gorin A, Brizuela S, Cheng QJ, Hoffmann A. IRF1 cooperates with ISGF3 or GAF to form innate immune de novo enhancers in macrophages. Sci Signal. 2025 Jan 07; 18(868):eado8860. view on PubMed

Guerrero P, Bono C, Sobén M, Guiu A, Cheng QJ, Gil ML, Yáñez A. GM-CSF receptor expression determines opposing innate memory phenotypes at different stages of myelopoiesis. Blood. 2024 06 27; 143(26):2763-2777. view on PubMed

Cheng QJ, Farrell K, Fenn J, Ma Z, Makanani SK, Siemsen J. Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks. Sci Rep. 2024 01 17; 14(1):1454. view on PubMed

Wilder CL, Lefaudeux D, Mathenge R, Kishimoto K, Zuniga Munoz A, Nguyen MA, Meyer AS, Cheng QJ, Hoffmann A. A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes. Mol Syst Biol. 2023 05 09; 19(5):e11294. view on PubMed

Kim J, Sheu KM, Cheng QJ, Hoffmann A, Enciso G. Stochastic models of nucleosome dynamics reveal regulatory rules of stimulus-induced epigenome remodeling. Cell Rep. 2022 07 12; 40(2):111076. view on PubMed

Cheng QJ, Ohta S, Sheu KM, Spreafico R, Adelaja A, Taylor B, Hoffmann A. NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages. Science. 2021 06 18; 372(6548):1349-1353. view on PubMed

Kishimoto K, Wilder CL, Buchanan J, Nguyen M, Okeke C, Hoffmann A, Cheng QJ. High Dose IFN-β Activates GAF to Enhance Expression of ISGF3 Target Genes in MLE12 Epithelial Cells. Front Immunol. 2021; 12:651254. view on PubMed

Mitchell S, Mercado EL, Adelaja A, Ho JQ, Cheng QJ, Ghosh G, Hoffmann A. An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms. Front Immunol. 2019; 10:1425. view on PubMed

Cheng QJ, Engelage EM, Grogan TR, Currier JS, Hoffman RM. Who Provides Primary Care? An Assessment of HIV Patient and Provider Practices and Preferences. J AIDS Clin Res. 2014 Nov; 5(11). view on PubMed