Loading Events

« All Events

  • This event has passed.

MBI Thursday Research Seminar | Sabine Petry, Ph.D. | Hosted by Margot Quinlan

April 1 @ 9:00 am - 10:00 am

“How to make microtubules and build the cytoskeleton”
Sabine Petry, Ph.D.

Associate Professor, Molecular Biology
Princeton University

Abstract:
How does a cell construct its microtubule cytoskeleton? According to Feynman’s principle “what I cannot create, I do not understand”, my lab pursues this question by building the chromosome segregation machinery from scratch. I will first tell you how the microtubule framework is generated in a cell. Upon deciphering the function of the most important microtubule accessory proteins, I will present how we use those building blocks to reconstitute a spindle substructure in vitro and determine its building plan. Finally, I will outline how we combine spindle substructures like pieces of a puzzle to assemble and thereby understand a functioning spindle that segregates chromosomes.

By studying how the MT cytoskeleton is built, I hope to help explain how hundreds of proteins can self-assemble on the nm scale into a complex molecular machine 1000-fold larger than its constituents, a challenge for the biochemistry of the 21st century

 

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

Details

Date:
April 1
Time:
9:00 am - 10:00 am
Event Categories:
,

Organizer

Molecular Biology Institute
Phone:
310-825-1018
Email:
mbiasst@lifesci.ucla.edu
Website:
http://www.mbi.ucla.edu

Venue

Zoom

Details

Date:
April 1
Time:
9:00 am - 10:00 am
Event Categories:
,

Organizer

Molecular Biology Institute
Phone:
310-825-1018
Email:
mbiasst@lifesci.ucla.edu
Website:
http://www.mbi.ucla.edu

Venue

Zoom