Tamer Sallam* – Molecular Biology Institute

Publications:

Zhou Z, Moore TM, Strumwasser AR, Ribas V, Iwasaki H, Morrow N, Ma A, Tran PH, Wanagat J, de Aguiar Vallim TQ, Clifford B, Zhang Z, Sallam T, Parks BW, Reue K, Shirihai O, Acin-Perez R, Morselli M, Pellegrini M, Mahata SK, Norheim F, Zhou M, Seldin MM, Lusis AJ, Lee CC, Goodarzi MO, Rotter JI, Hansen JR, Drucker B, Sagendorf TJ, Adkins JN, Sanford JA, DeMayo FJ, Hewitt SC, Korach KS, Hevener AL. Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males. Cell Rep Med. 2025 May 02; 102116. view on PubMed

De Siqueira MK, Li G, Zhao Y, Wang S, Ahn IS, Tamboline M, Hildreth AD, Larios J, Schcolnik-Cabrera A, Nouhi Z, Zhang Z, Tol MJ, Pandey V, Xu S, O'Sullivan TE, Mack JJ, Tontonoz P, Sallam T, Wohlschlegel JA, Hulea L, Xiao X, Yang X, Villanueva CJ. PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity. Cell Rep. 2024 12 24; 43(12):114945. view on PubMed

Wang D, Baghoomian A, Zhang Z, Cui Y, Whang EC, Li X, Fraga J, Spellman RA, Dong TS, Li W, Gupta A, Benhammou JN, Sallam T. Hepatic lipopolysaccharide binding protein partially uncouples inflammation from fibrosis in MAFLD. J Clin Invest. 2024 Sep 03; 134(17). view on PubMed

Li X, Sallam T. A (cholesterol) crystal clear path to inflammasome activation in atherosclerosis. J Lipid Res. 2024 06; 65(6):100554. view on PubMed

Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, Jaffrey SR, Reue K, Chen J, Sallam T. Author Correction: Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits. Nat Metab. 2023 Mar; 5(3):530. view on PubMed

Bhatnagar R, Dixit NM, Yang EH, Sallam T. Cancer therapy's impact on lipid metabolism: Mechanisms and future avenues. Front Cardiovasc Med. 2022; 9:925816. view on PubMed

Vuong JT, Stein-Merlob AF, Nayeri A, Sallam T, Neilan TG, Yang EH. Immune Checkpoint Therapies and Atherosclerosis: Mechanisms and Clinical Implications: JACC State-of-the-Art Review. J Am Coll Cardiol. 2022 02 15; 79(6):577-593. view on PubMed

Repetti GG, Sallam T. Editorial commentary: The promise of MicroRNAs in myocardial infarction: Mirage or reality? Trends Cardiovasc Med. 2023 05; 33(4):202-203. view on PubMed

Kallapur A, Sallam T. Pharmacotherapy in familial hypercholesterolemia - Current state and emerging paradigms. Trends Cardiovasc Med. 2023 04; 33(3):170-179. view on PubMed

Kan RL, Chen J, Sallam T. Crosstalk between epitranscriptomic and epigenetic mechanisms in gene regulation. Trends Genet. 2022 02; 38(2):182-193. view on PubMed

Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, Jaffrey SR, Reue K, Chen J, Sallam T. Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits. Nat Metab. 2021 07; 3(7):940-953. view on PubMed

Wang D, Sallam T. Where in the (lncRNA) World Is CARMN?: Safeguarding Against Vascular Dysfunction. Circ Res. 2021 04 30; 128(9):1276-1278. view on PubMed

Sallam T. Cardiovascular Outcomes in Systemic Lupus Erythematosus: Are We Dropping the Anchor or Dropping the Ball? J Am Coll Cardiol. 2021 04 13; 77(14):1728-1730. view on PubMed

Middlekauff HR, William KJ, Su B, Haptonstall K, Araujo JA, Wu X, Kim J, Sallam T. Changes in lipid composition associated with electronic cigarette use. J Transl Med. 2020 10 07; 18(1):379. view on PubMed

Trevillyan JM, Moser C, Currier JS, Sallam T. Immune Biomarkers in the Prediction of Future Myocardial Infarctions in People With Human Immunodeficiency Virus. Clin Infect Dis. 2020 04 10; 70(8):1764-1767. view on PubMed

Zhang Z, Feng AC, Salisbury D, Liu X, Wu X, Kim J, Lapina I, Wang D, Lee B, Fraga J, Pan C, Williams KJ, Lusis AJ, Scumpia P, Sallam T. Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice. Nat Commun. 2020 02 20; 11(1):984. view on PubMed

Cheng J, Cheng A, Clifford BL, Wu X, Hedin U, Maegdefessel L, Pamir N, Sallam T, Tarling EJ, de Aguiar Vallim TQ. MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice. Arterioscler Thromb Vasc Biol. 2020 02; 40(2):412-425. view on PubMed

Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019 07; 25:50-63. view on PubMed

Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST. PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. Antioxidants (Basel). 2019 Jan 11; 8(1). view on PubMed

Sallam T, Tontonoz P. Lnc-ing microRNA activity to atheroprotection. Nat Metab. 2019 Jan; 1(1):10-11. view on PubMed

Zhang Z, Salisbury D, Sallam T. Long Noncoding RNAs in Atherosclerosis: JACC Review Topic of the Week. J Am Coll Cardiol. 2018 11 06; 72(19):2380-2390. view on PubMed

Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nat Med. 2018 03; 24(3):304-312. view on PubMed

Sallam T, Sandhu J, Tontonoz P. Long Noncoding RNA Discovery in Cardiovascular Disease: Decoding Form to Function. Circ Res. 2018 01 05; 122(1):155-166. view on PubMed

Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018 01 11; 172(1-2):218-233.e17. view on PubMed

Zhang L, Rajbhandari P, Priest C, Sandhu J, Wu X, Temel R, Castrillo A, de Aguiar Vallim TQ, Sallam T, Tontonoz P. Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. Elife. 2017 10 25; 6. view on PubMed

Tontonoz P, Wu X, Jones M, Zhang Z, Salisbury D, Sallam T. Long Noncoding RNA Facilitated Gene Therapy Reduces Atherosclerosis in a Murine Model of Familial Hypercholesterolemia. Circulation. 2017 08 22; 136(8):776-778. view on PubMed

Watson KE, Sallam T. MY APPROACH to the Patient With Memory Loss Who Needs a Statin. Trends Cardiovasc Med. 2017 02; 27(2):158-159. view on PubMed

Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature. 2016 06 02; 534(7605):124-8. view on PubMed

Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. Int J Obes (Lond). 2016 09; 40(9):1424-34. view on PubMed

Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell Metab. 2015 Feb 03; 21(2):334-347. view on PubMed

Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. J Lipid Res. 2014 06; 55(6):1120-30. view on PubMed

Edris A, Sallam T, Traina MI. A wrong turn in embryologic development: a case of a primary right ventricular intracardiac tumor. J Am Coll Cardiol. 2014 Apr 08; 63(13):e29. view on PubMed

Sallam T, Watson KE. Predictors of cardiovascular risk in women. Womens Health (Lond). 2013 Sep; 9(5):491-8. view on PubMed

Sallam T, Tobis J. Rebuttal. Catheter Cardiovasc Interv. 2013 Sep 01; 82(3):427. view on PubMed

Sallam T, Cheng H, Demer LL, Tintut Y. Regulatory circuits controlling vascular cell calcification. Cell Mol Life Sci. 2013 Sep; 70(17):3187-97. view on PubMed

Sallam T, Levi D, Tobis J. Coil embolization of left coronary artery pseudoaneurysms arising as a complication of percutaneous coronary intervention. Catheter Cardiovasc Interv. 2012 Dec 01; 80(7):1228-31. view on PubMed

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