Hrishikesh Kulkarni
Hrishikesh S. Kulkarni, MD, MSCI, a physician-scientist at UCLA in the Division of Pulmonary, Critical Care and Sleep Medicine, and a member of the Immunology, Inflammation, Infection, and Transplantation (I3T) Research Theme, holds the Dr. Allan J. Swartz and Roslyn Holt Swartz Women's Lung Health Endowed Chair. The overarching goal of his program is to determine how locally active innate immune proteins can be harnessed to mitigate ALI risk in various settings such as infection and lung transplantation, to ultimately reduce the burden of end-stage lung disease. A major focus of their work involves distinguishing locally-derived complement proteins in the lung from those present in the blood, and how they modulate ALI. His laboratory has established in vitro and in vivo models to dissect tissue-specific sources of complement proteins that can be harnessed as therapeutics to mitigate ALI. Additionally, they leverage a robust biorepository of lung tissue, bronchial fluid and DNA from patients to guide and validate their research.
Websites:
Lab Website
Physician Profile
Jonsson Comprehensive Cancer Center Page
Research Interests:
Immunology, Transplantation, ARDS, Lung injury, Pneumonia, Complement,Publications:
Shankar NR, Garnica L, Stahlschmidt E, Gelman AE, Byers D, Kulkarni H. Characteristics of Human Donor Lungs Utilized for Research. Am J Respir Cell Mol Biol. 2025 May 02. view on PubMed
Liao F, Zhou D, Cano M, Liu Z, Scozzi D, Tague LK, Byers DE, Li W, Sivapackiam J, Sharma V, Krupnick AS, Frank DW, Kreisel D, Kulkarni HS, Hachem RR, Gelman AE. Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection. Sci Transl Med. 2025 Feb 05; 17(784):eadp1349. view on PubMed
Kulkarni HS, Tague LK, Calabrese DR, Liao F, Liu Z, Garnica L, Shankar N, Wu X, Kulkarni DH, Bernardt C, Byers D, Chen C, Huang HJ, Witt CA, Hachem RR, Kreisel D, Atkinson JP, Greenland JR, Gelman AE. Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation. bioRxiv. 2024 Nov 18. view on PubMed
Lehmann M, Krishnan R, Sucre J, Kulkarni HS, Pineda RH, Anderson C, Banovich NE, Behrsing HP, Dean CH, Haak A, Gosens R, Kaminski N, Zagorska A, Koziol-White C, Metcalf JP, Kim YH, Loebel C, Neptune E, Noel A, Raghu G, Sewald K, Sharma A, Suki B, Sperling A, Tatler A, Turner S, Rosas IO, van Ry P, Wille T, Randell SH, Pryhuber G, Rojas M, Bourke J, Königshoff M. Precision Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research. An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2024 Nov 05. view on PubMed
Earhart AP, Alburquerque RA, Starick M, Nallapu A, Garnica L, Ozanturk AN, Maurya RK, Wu X, Haspel JA, Kulkarni HS. The C3-C3aR axis modulates trained immunity in alveolar macrophages. bioRxiv. 2024 Nov 05. view on PubMed
Earhart AP, Kulkarni HS. Monocytes: See One Queuing Local Adaptive Immune Responses to Respiratory Viruses. Am J Respir Cell Mol Biol. 2024 Sep; 71(3):259-261. view on PubMed
Shankar NR, Garnica L, Stahlschmidt E, Byers D, Kulkarni H. Characteristics of human donor lungs utilized for research. bioRxiv. 2024 Aug 12. view on PubMed
Kulkarni DH, Starick M, Aponte Alburquerque R, Kulkarni HS. Local complement activation and modulation in mucosal immunity. Mucosal Immunol. 2024 Aug; 17(4):739-751. view on PubMed
Kulkarni HS. Hexamerization: explaining the original sin of IgG-mediated complement activation in acute lung injury. J Clin Invest. 2024 Jun 03; 134(11). view on PubMed
Sahu SK, Maurya RK, Kulkarni HS. The Role of Complement Component C3 in Protection Against Pseudomonas Pneumonia-Induced Lung Injury. DNA Cell Biol. 2024 Apr; 43(4):153-157. view on PubMed
Kulkarni DH, Rusconi B, Floyd AN, Joyce EL, Talati KB, Kousik H, Alleyne D, Harris DL, Garnica L, McDonough R, Bidani SS, Kulkarni HS, Newberry EP, McDonald KG, Newberry RD. Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development. Gut Microbes. 2023 12; 15(2):2284240. view on PubMed
January SE, Hubbard J, Fester KA, Dubrawka CA, Vazquez Guillamet R, Kulkarni HS, Hachem RR. Impact of Angiotensin Blockade on Development of Chronic Lung Allograft Dysfunction. J Pharm Pract. 2024 Oct; 37(5):1170-1174. view on PubMed
Moore BB, Ballinger MN, Bauer NN, Blackwell TS, Borok Z, Budinger GRS, Camoretti-Mercado B, Erzurum SC, Himes BE, Keshamouni VG, Kulkarni HS, Mallampalli RK, Mariani TJ, Martinez FJ, McCombs JE, Newcomb DC, Johnston RA, O'Reilly MA, Prakash YS, Ridge KM, Sime PJ, Sperling AI, Violette S, Wilkes DS, Königshoff M. Building Career Paths for Ph.D., Basic and Translational Scientists in Clinical Departments in the United States: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2023 08; 20(8):1077-1087. view on PubMed
January SE, Fester KA, Halverson LP, Witt CA, Byers DE, Vazquez-Guillamet R, Alexander-Brett J, Tague LK, Kreisel D, Gelman A, Puri V, Bahena RN, Takahashi T, Hachem RR, Kulkarni HS. Tocilizumab for antibody-mediated rejection treatment in lung transplantation. J Heart Lung Transplant. 2023 10; 42(10):1353-1357. view on PubMed
Terada Y, Takahashi T, Hachem RR, Liu J, Witt CA, Byers DE, Guillamet RV, Kulkarni HS, Nava RG, Kozower BD, Meyers BF, Pasque MK, Patterson GA, Marklin GF, Eghtesady P, Kreisel D, Puri V. Characteristics of donor lungs declined on site and impact of lung allocation policy change. J Thorac Cardiovasc Surg. 2023 11; 166(5):1347-1358.e11. view on PubMed
Annane D, Pittock SJ, Kulkarni HS, Pickering BW, Khoshnevis MR, Siegel JL, Powell CA, Castro P, Fujii T, Dunn D, Smith K, Mitter S, Kazani S, Kulasekararaj A. Intravenous ravulizumab in mechanically ventilated patients hospitalised with severe COVID-19: a phase 3, multicentre, open-label, randomised controlled trial. Lancet Respir Med. 2023 Dec; 11(12):1051-1063. view on PubMed
Terada Y, Hachem RR, Pasque MK, Kulkarni HS, Witt CA, Byers DE, Guillamet RV, Nava RG, Kozower BD, Meyers BF, Patterson GA, Kreisel D, Puri V, Takahashi T. Pulmonary Carcinoid Tumorlet in the Explanted Lungs for Lung Transplantation: A Case Series of 15 Patients. Transplant Proc. 2023 Mar; 55(2):446-448. view on PubMed
Sahu SK, Ozantürk AN, Kulkarni DH, Ma L, Barve RA, Dannull L, Lu A, Starick M, McPhatter J, Garnica L, Sanfillipo-Burchman M, Kunen J, Wu X, Gelman AE, Brody SL, Atkinson JP, Kulkarni HS. Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury. Sci Immunol. 2023 02 03; 8(80):eabp9547. view on PubMed
Liu Z, Liao F, Zhu J, Zhou D, Heo GS, Leuhmann HP, Scozzi D, Parks A, Hachem R, Byers DE, Tague LK, Kulkarni HS, Cano M, Wong BW, Li W, Huang HJ, Krupnick AS, Kreisel D, Liu Y, Gelman AE. Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome. J Clin Invest. 2022 10 03; 132(19). view on PubMed
Shepherd HM, Terada Y, Takahashi T, Pasque MK, Kulkarni HS, Guillamet RV, Witt CA, Nava RG, Puri V, Kreisel D, Patterson GA, Hachem RR. Acute Interstitial Pneumonia (Hamman-Rich Syndrome) in Lung Transplantation: A Case Series. Transplant Proc. 2022 Oct; 54(8):2313-2316. view on PubMed
Kulkarni HS, Lee JS, Downey GP, Matute-Bello G. Reply: Experimental Acute Lung Injury in Animals: With Age Comes Knowledge. Am J Respir Cell Mol Biol. 2022 08; 67(2):267. view on PubMed
Yang Z, Takahashi T, Terada Y, Meyers BF, Kozower BD, Patterson GA, Nava RG, Hachem RR, Witt CA, Byers DE, Kulkarni HS, Guillamet RV, Yan Y, Chang SH, Kreisel D, Puri V. A comparison of outcomes after lung transplantation between European and North American centers. J Heart Lung Transplant. 2022 12; 41(12):1729-1735. view on PubMed
Terada Y, Takahashi T, Hachem RR, Liu J, Witt CA, Byers DE, Guillamet RV, Kulkarni HS, Nava RG, Kozower BD, Meyers BF, Pasque MK, Patterson GA, Kreisel D, Puri V. Clinical features and outcomes of unplanned single lung transplants. J Thorac Cardiovasc Surg. 2022 12; 164(6):1650-1659.e3. view on PubMed
Kulkarni HS, Lee JS, Bastarache JA, Kuebler WM, Downey GP, Albaiceta GM, Altemeier WA, Artigas A, Bates JHT, Calfee CS, Dela Cruz CS, Dickson RP, Englert JA, Everitt JI, Fessler MB, Gelman AE, Gowdy KM, Groshong SD, Herold S, Homer RJ, Horowitz JC, Hsia CCW, Kurahashi K, Laubach VE, Looney MR, Lucas R, Mangalmurti NS, Manicone AM, Martin TR, Matalon S, Matthay MA, McAuley DF, McGrath-Morrow SA, Mizgerd JP, Montgomery SA, Moore BB, Noël A, Perlman CE, Reilly JP, Schmidt EP, Skerrett SJ, Suber TL, Summers C, Suratt BT, Takata M, Tuder R, Uhlig S, Witzenrath M, Zemans RL, Matute-Bello G. Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2022 02; 66(2):e1-e14. view on PubMed
Sahu SK, Kulkarni DH, Ozanturk AN, Ma L, Kulkarni HS. Emerging roles of the complement system in host-pathogen interactions. Trends Microbiol. 2022 04; 30(4):390-402. view on PubMed
Tague LK, Bedair B, Witt C, Byers DE, Vazquez-Guillamet R, Kulkarni H, Alexander-Brett J, Nava R, Puri V, Kreisel D, Trulock EP, Gelman A, Hachem RR. Lung protective ventilation based on donor size is associated with a lower risk of severe primary graft dysfunction after lung transplantation. J Heart Lung Transplant. 2021 10; 40(10):1212-1222. view on PubMed
Kulkarni HS, Lease ED. Can we decloak how infections drive complications after lung transplantation? J Heart Lung Transplant. 2021 09; 40(9):960-962. view on PubMed
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection. Sci Immunol. 2021 05 13; 6(59). view on PubMed
Randhawa SK, Yang Z, Morkan DB, Yan Y, Chang SH, Hachem RR, Witt CA, Byers DE, Kulkarni HS, Guillamet RV, Kozower BD, Nava RG, Meyers BF, Patterson GA, Kreisel D, Puri V. One-Year Survival Worse for Lung Retransplants Relative to Primary Lung Transplants. Ann Thorac Surg. 2022 04; 113(4):1265-1273. view on PubMed
Yang Z, Subramanian MP, Yan Y, Meyers BF, Kozower BD, Patterson GA, Nava RG, Hachem RR, Witt CA, Pasque MK, Byers DE, Kulkarni HS, Kreisel D, Itoh A, Puri V. The Impact of Center Volume on Outcomes in Lung Transplantation. Ann Thorac Surg. 2022 03; 113(3):911-917. view on PubMed
Bery AI, Kulkarni HS, Kreisel D. Editorial: COVID-19 immunology and organ transplantation. Curr Opin Organ Transplant. 2021 04 01; 26(2):258-265. view on PubMed
Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection. bioRxiv. 2021 Feb 23. view on PubMed
Scozzi D, Cano M, Ma L, Zhou D, Zhu JH, O'Halloran JA, Goss C, Rauseo AM, Liu Z, Sahu SK, Peritore V, Rocco M, Ricci A, Amodeo R, Aimati L, Ibrahim M, Hachem R, Kreisel D, Mudd PA, Kulkarni HS, Gelman AE. Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19. JCI Insight. 2021 02 22; 6(4). view on PubMed
Vazquez Guillamet MC, Kulkarni HS, Montes K, Samant M, Shaikh PA, Betthauser K, Mudd PA, Reynolds D, O'Halloran J, Lyons P, McEvoy C, Vazquez Guillamet R. Interleukin-6 Trajectory and Secondary Infections in Mechanically Ventilated Patients With Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Treated With Interleukin-6 Receptor Blocker. Crit Care Explor. 2021 Feb; 3(2):e0343. view on PubMed
Frye CC, Gauthier JM, Bery A, Gerull WD, Morkan DB, Liu J, Shea Harrison M, Terada Y, Van Zanden JE, Marklin GF, Pasque MK, Nava RG, Meyers BF, Patterson AG, Kozower BD, Hachem R, Byers D, Witt C, Kulkarni H, Kreisel D, Puri V. Donor management using a specialized donor care facility is associated with higher organ utilization from drug overdose donors. Clin Transplant. 2021 03; 35(3):e14178. view on PubMed
Kulkarni HS, Atkinson JP. Targeting complement activation in COVID-19. Blood. 2020 10 29; 136(18):2000-2001. view on PubMed
Terada Y, Gauthier JM, Pasque MK, Takahashi T, Liu J, Nava RG, Hachem RR, Witt CA, Byers DE, Vazquez Guillamet R, Kozower BD, Meyers BF, Aguilar PR, Kulkarni HS, Patterson GA, Kreisel D, Puri V. Clinical Outcomes of Lung Transplants From Donors With Unexpected Pulmonary Embolism. Ann Thorac Surg. 2021 08; 112(2):387-394. view on PubMed
Yang Z, Takahashi T, Gerull WD, Hamilton C, Subramanian MP, Liu J, Meyers BF, Kozower BD, Patterson GA, Nava RG, Hachem RR, Witt CA, Aguilar PR, Pasque MK, Byers DE, Kulkarni HS, Kreisel D, Puri V. Impact of Nighttime Lung Transplantation on Outcomes and Costs. Ann Thorac Surg. 2021 07; 112(1):206-213. view on PubMed
Kulkarni HS, Ramphal K, Ma L, Brown M, Oyster M, Speckhart KN, Takahashi T, Byers DE, Porteous MK, Kalman L, Hachem RR, Rushefski M, McPhatter J, Cano M, Kreisel D, Scavuzzo M, Mittler B, Cantu E, Pilely K, Garred P, Christie JD, Atkinson JP, Gelman AE, Diamond JM. Local complement activation is associated with primary graft dysfunction after lung transplantation. JCI Insight. 2020 09 03; 5(17). view on PubMed
Gerull WD, Yang Z, Kreisel D, Nava R, Meyers BF, Patterson GA, Kozower BD, Hachem RR, Witt C, Byers D, Kulkarni H, Guillamet RV, Marklin G, Puri V. Local versus distant lung donor procurement does not influence short-term clinical outcomes. J Thorac Cardiovasc Surg. 2021 Oct; 162(4):1284-1293.e4. view on PubMed
Frye CC, Bery AI, Kreisel D, Kulkarni HS. Sterile inflammation in thoracic transplantation. Cell Mol Life Sci. 2021 Jan; 78(2):581-601. view on PubMed
Java A, Apicelli AJ, Liszewski MK, Coler-Reilly A, Atkinson JP, Kim AH, Kulkarni HS. The complement system in COVID-19: friend and foe? JCI Insight. 2020 08 06; 5(15). view on PubMed
Scozzi D, Cano M, Ma L, Zhou D, Zhu JH, O'Halloran JA, Goss C, Rauseo AM, Liu Z, Peritore V, Rocco M, Ricci A, Amodeo R, Aimati L, Ibrahim M, Hachem R, Kreisel D, Mudd PA, Kulkarni HS, Gelman AE. Circulating Mitochondrial DNA is an Early Indicator of Severe Illness and Mortality from COVID-19. bioRxiv. 2020 Jul 30. view on PubMed
Bain W, Li H, van der Geest R, Moore SR, Olonisakin TF, Ahn B, Papke E, Moghbeli K, DeSensi R, Rapport S, Saul M, Hulver M, Xiong Z, Mallampalli RK, Ray P, Morris A, Ma L, Doi Y, Zhang Y, Kitsios GD, Kulkarni HS, McVerry BJ, Ferreira VP, Nouraie M, Lee JS. Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness. Am J Respir Crit Care Med. 2020 07 15; 202(2):230-240. view on PubMed
Kulkarni HS, Scozzi D, Gelman AE. Recent advances into the role of pattern recognition receptors in transplantation. Cell Immunol. 2020 05; 351:104088. view on PubMed
Kulkarni HS, Tsui K, Sunder S, Ganninger A, Tague LK, Witt CA, Byers DE, Trulock EP, Nava R, Puri V, Kreisel D, Mohanakumar T, Gelman AE, Hachem RR. Pseudomonas aeruginosa and acute rejection independently increase the risk of donor-specific antibodies after lung transplantation. Am J Transplant. 2020 04; 20(4):1028-1038. view on PubMed
January SE, Fester KA, Bain KB, Kulkarni HS, Witt CA, Byers DE, Alexander-Brett J, Trulock EP, Hachem RR. Rabbit antithymocyte globulin for the treatment of chronic lung allograft dysfunction. Clin Transplant. 2019 10; 33(10):e13708. view on PubMed
Kulkarni HS, Korenblat KM, Kreisel D. Expanding the donor pool for lung transplantation using HCV-positive donors. J Thorac Dis. 2019 Sep; 11(Suppl 15):S1942-S1946. view on PubMed
Tague LK, Witt CA, Byers DE, Yusen RD, Aguilar PR, Kulkarni HS, Bain KB, Fester KA, Puri V, Kreisel D, Mohanakumar T, Trulock EP, Hachem RR. Association between Allosensitization and Waiting List Outcomes among Adult Lung Transplant Candidates in the United States. Ann Am Thorac Soc. 2019 07; 16(7):846-852. view on PubMed
Tague LK, Byers DE, Hachem R, Kreisel D, Krupnick AS, Kulkarni HS, Chen C, Huang HJ, Gelman A. Impact of SLCO1B3 polymorphisms on clinical outcomes in lung allograft recipients receiving mycophenolic acid. Pharmacogenomics J. 2020 02; 20(1):69-79. view on PubMed
Elvington M, Liszewski MK, Liszewski AR, Kulkarni HS, Hachem RR, Mohanakumar T, Kim AHJ, Atkinson JP. Development and Optimization of an ELISA to Quantitate C3(H 2 O) as a Marker of Human Disease. Front Immunol. 2019; 10:703. view on PubMed
Kulkarni H, Parthasarathy S. Is positive airway pressure therapy underutilized in chronic obstructive pulmonary disease patients? Expert Rev Respir Med. 2019 05; 13(5):407-415. view on PubMed
Kulkarni HS, Elvington ML, Perng YC, Liszewski MK, Byers DE, Farkouh C, Yusen RD, Lenschow DJ, Brody SL, Atkinson JP. Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death. Am J Respir Cell Mol Biol. 2019 02; 60(2):144-157. view on PubMed
Scozzi D, Ibrahim M, Liao F, Lin X, Hsiao HM, Hachem R, Tague LK, Ricci A, Kulkarni HS, Huang HJ, Sugimoto S, Krupnick AS, Kreisel D, Gelman AE. Mitochondrial damage-associated molecular patterns released by lung transplants are associated with primary graft dysfunction. Am J Transplant. 2019 05; 19(5):1464-1477. view on PubMed
Kulkarni HS, Diamond JM, Schrepfer S, Cantu E. Exosomal profiling in cardiac allograft rejection: Best basic science article in 2018. J Heart Lung Transplant. 2019 03; 38(3):334-336. view on PubMed
Kulkarni HS, Cherikh WS, Chambers DC, Garcia VC, Hachem RR, Kreisel D, Puri V, Kozower BD, Byers DE, Witt CA, Alexander-Brett J, Aguilar PR, Tague LK, Furuya Y, Patterson GA, Trulock EP, Yusen RD. Bronchiolitis obliterans syndrome-free survival after lung transplantation: An International Society for Heart and Lung Transplantation Thoracic Transplant Registry analysis. J Heart Lung Transplant. 2019 01; 38(1):5-16. view on PubMed
Kulkarni HS, Liszewski MK, Brody SL, Atkinson JP. The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target? J Allergy Clin Immunol. 2018 05; 141(5):1582-1586.e1. view on PubMed
Kulkarni HS, Witt CA. Voriconazole in lung transplant recipients - how worried should we be? Am J Transplant. 2018 01; 18(1):5-6. view on PubMed
Elvington M, Liszewski MK, Bertram P, Kulkarni HS, Atkinson JP. A C3(H20) recycling pathway is a component of the intracellular complement system. J Clin Invest. 2017 Mar 01; 127(3):970-981. view on PubMed
Liszewski MK, Elvington M, Kulkarni HS, Atkinson JP. Complement's hidden arsenal: New insights and novel functions inside the cell. Mol Immunol. 2017 04; 84:2-9. view on PubMed
Crouch R, Kulkarni HS. Pulmonary Exercise Training before and after Lung Transplantation. Am J Respir Crit Care Med. 2016 09 01; 194(5):P9-P10. view on PubMed
Slatore CG, Kulkarni HS, Corn J, Sockrider M. Improving Health Literacy. The New American Thoracic Society Guidelines for Patient Education Materials. Ann Am Thorac Soc. 2016 Aug; 13(8):1208-11. view on PubMed
Kulkarni HS, Bemiss BC, Hachem RR. Antibody-mediated Rejection in Lung Transplantation. Curr Transplant Rep. 2015 Dec; 2(4):316-323. view on PubMed
Kulkarni HS, Chey WD, Mookherjee S, Saint S, Bump GM. Taking the detour. J Hosp Med. 2015 Oct; 10(10):686-90. view on PubMed
Kulkarni HS, Gutierrez FR, Despotovic V, Russell TD. A 43-year-old man with antisynthetase syndrome presenting with acute worsening of dyspnea. Chest. 2015 Jun; 147(6):e215-e219. view on PubMed
Kulkarni HS, Rosenbluth DB. Cavitary lung nodules in a patient with prior squamous cell carcinoma of the submandibular gland. Am J Respir Crit Care Med. 2014 Dec 15; 190(12):1447-8. view on PubMed
Kulkarni HS, Khoury CC. Sepsis associated with Lactobacillus bacteremia in a patient with ischemic colitis. Indian J Crit Care Med. 2014 Sep; 18(9):606-8. view on PubMed
Kulkarni HS, Guzy RD, McEvoy C. YKL-40 in pediatric asthma, MUC5B promoter polymorphism in idiopathic pulmonary fibrosis, and esmolol in septic shock. Am J Respir Crit Care Med. 2014 May 01; 189(9):1138-40. view on PubMed
Nigwekar SU, Kulkarni H, Thakar CV. Natriuretic peptides in the management of solid organ transplantation associated acute kidney injury: a systematic review and meta-analysis. Int J Nephrol. 2013; 2013:949357. view on PubMed
Chandra D, Wise RA, Kulkarni HS, Benzo RP, Criner G, Make B, Slivka WA, Ries AL, Reilly JJ, Martinez FJ, Sciurba FC, NETT Research Group. Optimizing the 6-min walk test as a measure of exercise capacity in COPD. Chest. 2012 Dec; 142(6):1545-1552. view on PubMed
Kasi PM, Tawbi HA, Oddis CV, Kulkarni HS. Clinical review: Serious adverse events associated with the use of rituximab - a critical care perspective. Crit Care. 2012 Aug 31; 16(4):231. view on PubMed
Naik C, Kulkarni H, Darabi A, Bhanot N. Ochrobactrum anthropi: a rare cause of pneumonia. J Infect Chemother. 2013 Feb; 19(1):162-5. view on PubMed
Kulkarni HS, Kasi PM. Rituximab and cytokine release syndrome. Case Rep Oncol. 2012 Jan; 5(1):134-41. view on PubMed
Chandra D, Kulkarni HS, Sciurba F. Learning from the learning effect in the six-minute-walk test. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):684; author reply 684-5. view on PubMed
Kulkarni HS, Chandra D, Sciurba FC. Increase in walk distance is not enough evidence to add a walk to the 6-minute walk test. Eur Respir J. 2011 Nov; 38(5):1239-40; author's reply 1240-1. view on PubMed
Kulkarni HS, Kulkarni KR, Mallampalli A, Parkar SR, Karnad DR, Guntupalli KK. Comparison of anxiety, depression, and post-traumatic stress symptoms in relatives of ICU patients in an American and an Indian public hospital. Indian J Crit Care Med. 2011 Jul; 15(3):147-56. view on PubMed
Shin HS, Xu F, Bagchi A, Herrup E, Prakash A, Valentine C, Kulkarni H, Wilhelmsen K, Warren S, Hellman J. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J Immunol. 2011 Jan 15; 186(2):1119-30. view on PubMed
Kulkarni HS. Less-obvious predictors of post-ICU informal caregiver burden. Chest. 2010 Oct; 138(4):1024; author reply 1024-5. view on PubMed
Luo X, Zhou Y, Tao D, Yu Y, Hu J, Qiu F, Kulkarni H, Gong J. Usefulness of oral mucosal epithelial cell apoptosis rate in nutritional assessment. Nutrition. 2006 Oct; 22(10):1032-8. view on PubMed
Sideris EB, Walsh KP, Haddad JL, Chen CR, Ren SG, Kulkarni H. Occlusion of congenital ventricular septal defects by the buttoned device. "Buttoned device" Clinical Trials International Register. Heart. 1997 Mar; 77(3):276-9. view on PubMed
Taskar VS, Rupwate RU, Kulkarni H, Kamat SR. Effect of 3 week oxygen therapy on functional and haemodynamic parameters in chronic obstructive pulmonary disease. J Assoc Physicians India. 1990 Nov; 38(11):839-42. view on PubMed
