George Agak

Publications:

To TT, Oparaugo NC, Kheshvadjian AR, Nelson AM, Agak GW. Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection. Int J Mol Sci. 2024 Feb 07; 25(4). view on PubMed

Agak GW, Thiboutot DM, Zaenglein AL, Nelson AM. SLST D1 strains may contribute to skin health. Exp Dermatol. 2024 Jan; 33(1):e14968. view on PubMed

Nolan ZT, Banerjee K, Cong Z, Gettle SL, Longenecker AL, Kawasawa YI, Zaenglein AL, Thiboutot DM, Agak GW, Zhan X, Nelson AM. Treatment response to isotretinoin correlates with specific shifts in Cutibacterium acnes strain composition within the follicular microbiome. Exp Dermatol. 2023 07; 32(7):955-964. view on PubMed

Oparaugo NC, Ouyang K, Nguyen NPN, Nelson AM, Agak GW. Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers. Int J Mol Sci. 2023 Jan 12; 24(2). view on PubMed

Konate D, Diawara SI, Sogoba N, Shaffer J, Keita B, Cisse A, Sanogo I, Dicko I, Guindo MDA, Balam S, Traore A, Kante S, Dembele A, Kasse F, Denou L, Diakite SAS, Traore K, M'Baye Thiam S, Sanogo V, Toure M, Diarra A, Agak GW, Doumbia S, Diakite M. Effect of a fifth round of seasonal malaria chemoprevention in children aged 5-14 years in Dangassa, an area of long transmission in Mali. Parasite Epidemiol Control. 2023 Feb; 20:e00283. view on PubMed

Nguyen NPN, Oparaugo NC, Ouyang K, Agak GW. A protocol to detect human CD4+ T cell extracellular traps using scanning electron microscopy. STAR Protoc. 2023 03 17; 4(1):101932. view on PubMed

Nang'ole WF, Omu A, Ogeng'o JA, Agak GW. Do Mesenchymal Stem Cells Influence Keloid Recurrence? Stem Cells Cloning. 2022; 15:77-84. view on PubMed

Ouyang K, Zheng DX, Agak GW. T-Cell Mediated Immunity in Merkel Cell Carcinoma. Cancers (Basel). 2022 Dec 09; 14(24). view on PubMed

Schneider AM, Nolan ZT, Banerjee K, Paine AR, Cong Z, Gettle SL, Longenecker AL, Zhan X, Agak GW, Nelson AM. Evolution of the facial skin microbiome during puberty in normal and acne skin. J Eur Acad Dermatol Venereol. 2023 Jan; 37(1):166-175. view on PubMed

Ouyang K, Oparaugo N, Nelson AM, Agak GW. T Cell Extracellular Traps: Tipping the Balance Between Skin Health and Disease. Front Immunol. 2022; 13:900634. view on PubMed

Nangole FW, Agak G. The effects of negative pressure wound therapy on wounds with cerebrospinal fluid leakages. J Wound Care. 2022 Apr 02; 31(4):348-351. view on PubMed

Wanjala NF, Joseph G, Anthony M, Primus O, Ogeng'o JJ, Anzala O, Dohil I, Agak GW. Keloids: Does patients' sex influence the presentation and recurrence post-excision? J Plast Reconstr Aesthet Surg. 2022 Jan; 75(1):366-368. view on PubMed

Nangole FW, Ouyang K, Anzala O, Ogeng'o J, Agak GW, Zuriel D. Does Keloid Histology Influence Recurrence? Am J Dermatopathol. 2021 Sep 01; 43(9):642-646. view on PubMed

Nangole FW, Ouyang K, Anzala O, Ogengo J, Agak GW. Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease? J Inflamm Res. 2021; 14:2465-2470. view on PubMed

Agak GW, Mouton A, Teles RM, Weston T, Morselli M, Andrade PR, Pellegrini M, Modlin RL. Extracellular traps released by antimicrobial TH17 cells contribute to host defense. J Clin Invest. 2021 01 19; 131(2). view on PubMed

Nangole FW, Agak GW. Keloid pathophysiology: fibroblast or inflammatory disorders? JPRAS Open. 2019 Dec; 22:44-54. view on PubMed

Park AJ, Agak GW, Qin M, Hisaw LD, Pirouz A, Kao S, Marinelli LJ, Garbán HJ, Thiboutot D, Liu PT, Kim J. G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes. Ann Dermatol. 2017 Dec; 29(6):688-698. view on PubMed

Agak GW, Kao S, Ouyang K, Qin M, Moon D, Butt A, Kim J. Phenotype and Antimicrobial Activity of Th17 Cells Induced by Propionibacterium acnes Strains Associated with Healthy and Acne Skin. J Invest Dermatol. 2018 02; 138(2):316-324. view on PubMed

Yu Y, Champer J, Agak GW, Kao S, Modlin RL, Kim J. Different Propionibacterium acnes Phylotypes Induce Distinct Immune Responses and Express Unique Surface and Secreted Proteomes. J Invest Dermatol. 2016 11; 136(11):2221-2228. view on PubMed

Hisaw LD, Qin M, Park A, Agak GW, Pirouz A, Phan J, Fernandez C, Garbán HJ, Nelson A, Thiboutot D, Kim J. Antimicrobial Activity of Sebocytes against Propionibacterium acnes via Toll-Like Receptor 2 and Lysosomal Pathway. J Invest Dermatol. 2016 10; 136(10):2098-2101. view on PubMed

Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J, Friedman AJ. Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. J Invest Dermatol. 2015 Nov; 135(11):2723-2731. view on PubMed

Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL. Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes. J Invest Dermatol. 2015 Jun; 135(6):1581-1589. view on PubMed

Agak GW, Qin M, Nobe J, Kim MH, Krutzik SR, Tristan GR, Elashoff D, Garbán HJ, Kim J. Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D. J Invest Dermatol. 2014 Feb; 134(2):366-373. view on PubMed

Olugbile S, Villard V, Bertholet S, Jafarshad A, Kulangara C, Roussilhon C, Frank G, Agak GW, Felger I, Nebie I, Konate K, Kajava AV, Schuck P, Druilhe P, Spertini F, Corradin G. Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope. Vaccine. 2011 Sep 16; 29(40):7090-9. view on PubMed

Agak GW, Bejon P, Fegan G, Gicheru N, Villard V, Kajava AV, Marsh K, Corradin G. Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya. Vaccine. 2008 Apr 07; 26(16):1963-71. view on PubMed

Villard V, Agak GW, Frank G, Jafarshad A, Servis C, Nébié I, Sirima SB, Felger I, Arevalo-Herrera M, Herrera S, Heitz F, Bäcker V, Druilhe P, Kajava AV, Corradin G. Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif. PLoS One. 2007 Jul 25; 2(7):e645. view on PubMed