Diane Papazian
Publications:
Bavan S, Goodkin HP, Papazian DM. Altered closed state inactivation gating in Kv4.2 channels results in developmental and epileptic encephalopathies in human patients. Hum Mutat. 2022 09; 43(9):1286-1298. view on PubMed
Hsieh JY, Ulrich BN, Issa FA, Lin MA, Brown B, Papazian DM. Infant and adult SCA13 mutations differentially affect Purkinje cell excitability, maturation, and viability in vivo. Elife. 2020 07 09; 9. view on PubMed
Lin MA, Cannon SC, Papazian DM. Kv4.2 autism and epilepsy mutation enhances inactivation of closed channels but impairs access to inactivated state after opening. Proc Natl Acad Sci U S A. 2018 04 10; 115(15):E3559-E3568. view on PubMed
Hsieh JY, Papazian DM. In Vivo Analysis of Potassium Channelopathies: Loose Patch Recording of Purkinje Cell Firing in Living, Awake Zebrafish. Methods Mol Biol. 2018; 1684:237-252. view on PubMed
Duarri A, Lin MC, Fokkens MR, Meijer M, Smeets CJ, Nibbeling EA, Boddeke E, Sinke RJ, Kampinga HH, Papazian DM, Verbeek DS. Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner. Cell Mol Life Sci. 2015 Sep; 72(17):3387-99. view on PubMed
Hsieh JY, Ulrich B, Issa FA, Wan J, Papazian DM. Rapid development of Purkinje cell excitability, functional cerebellar circuit, and afferent sensory input to cerebellum in zebrafish. Front Neural Circuits. 2014; 8:147. view on PubMed
Lee H, Lin MC, Kornblum HI, Papazian DM, Nelson SF. Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation. Hum Mol Genet. 2014 Jul 01; 23(13):3481-9. view on PubMed
Issa FA, Mock AF, Sagasti A, Papazian DM. Spinocerebellar ataxia type 13 mutation that is associated with disease onset in infancy disrupts axonal pathfinding during neuronal development. Dis Model Mech. 2012 Nov; 5(6):921-9. view on PubMed
Minassian NA, Lin MC, Papazian DM. Altered Kv3.3 channel gating in early-onset spinocerebellar ataxia type 13. J Physiol. 2012 Apr 01; 590(7):1599-614. view on PubMed
Lin MC, Hsieh JY, Mock AF, Papazian DM. R1 in the Shaker S4 occupies the gating charge transfer center in the resting state. J Gen Physiol. 2011 Aug; 138(2):155-63. view on PubMed
Issa FA, Mazzochi C, Mock AF, Papazian DM. Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish. J Neurosci. 2011 May 04; 31(18):6831-41. view on PubMed
Figueroa KP, Waters MF, Garibyan V, Bird TD, Gomez CM, Ranum LP, Minassian NA, Papazian DM, Pulst SM. Frequency of KCNC3 DNA variants as causes of spinocerebellar ataxia 13 (SCA13). PLoS One. 2011 Mar 29; 6(3):e17811. view on PubMed
Issa FA, O'Brien G, Kettunen P, Sagasti A, Glanzman DL, Papazian DM. Neural circuit activity in freely behaving zebrafish (Danio rerio). J Exp Biol. 2011 Mar 15; 214(Pt 6):1028-38. view on PubMed
Mock AF, Richardson JL, Hsieh JY, Rinetti G, Papazian DM. Functional effects of spinocerebellar ataxia type 13 mutations are conserved in zebrafish Kv3.3 channels. BMC Neurosci. 2010 Aug 16; 11:99. view on PubMed
Lin MC, Abramson J, Papazian DM. Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. J Gen Physiol. 2010 May; 135(5):415-31. view on PubMed
Koag MC, Papazian DM. Voltage-dependent conformational changes of KVAP S4 segment in bacterial membrane environment. Channels (Austin). 2009 Sep-Oct; 3(5):356-65. view on PubMed
Papazian DM. S0, where is it? J Gen Physiol. 2008 Jun; 131(6):531-6. view on PubMed
Lin MC, Papazian DM. Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating. Channels (Austin). 2007 Nov-Dec; 1(6):429-37. view on PubMed
Richardson J, Blunck R, Ge P, Selvin PR, Bezanilla F, Papazian DM, Correa AM. Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15865-70. view on PubMed
Waters MF, Minassian NA, Stevanin G, Figueroa KP, Bannister JP, Nolte D, Mock AF, Evidente VG, Fee DB, Müller U, Dürr A, Brice A, Papazian DM, Pulst SM. Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes. Nat Genet. 2006 Apr; 38(4):447-51. view on PubMed
Bannister JP, Chanda B, Bezanilla F, Papazian DM. Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18718-23. view on PubMed
Silverman WR, Bannister JP, Papazian DM. Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel. Biophys J. 2004 Nov; 87(5):3110-21. view on PubMed
Myers MP, Khanna R, Lee EJ, Papazian DM. Voltage sensor mutations differentially target misfolded K+ channel subunits to proteasomal and non-proteasomal disposal pathways. FEBS Lett. 2004 Jun 18; 568(1-3):110-6. view on PubMed
Papazian DM. BK channels: the spring between sensor and gate. Neuron. 2004 Jun 10; 42(5):699-701. view on PubMed
Khanna R, Lee EJ, Papazian DM. Transient calnexin interaction confers long-term stability on folded K+ channel protein in the ER. J Cell Sci. 2004 Jun 15; 117(Pt 14):2897-908. view on PubMed
Lainé M, Papazian DM, Roux B. Critical assessment of a proposed model of Shaker. FEBS Lett. 2004 Apr 30; 564(3):257-63. view on PubMed
Lainé M, Lin MC, Bannister JP, Silverman WR, Mock AF, Roux B, Papazian DM. Atomic proximity between S4 segment and pore domain in Shaker potassium channels. Neuron. 2003 Jul 31; 39(3):467-81. view on PubMed
Silverman WR, Roux B, Papazian DM. Structural basis of two-stage voltage-dependent activation in K+ channels. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2935-40. view on PubMed
Papazian DM, Silverman WR, Lin MC, Tiwari-Woodruff SK, Tang CY. Structural organization of the voltage sensor in voltage-dependent potassium channels. Novartis Found Symp. 2002; 245:178-90; discussion 190-2, 261-4. view on PubMed
Papazian DM. Potassium channels: some assembly required. Neuron. 1999 May; 23(1):7-10. view on PubMed
