“Muscle Stem Heterogeneity and the Niche”
Andrew Brack, Ph.D.
Department of Orthopaedic Surgery
University of California, San Francisco
Originally from Liverpool, England, Dr. Brack graduated with a PhD in Molecular Biology and Biophysics from King’s College London. In 2008 he started his own lab at the Center for Regenerative Medicine, MGH, and Harvard University, were he focused on the property of quiescence within muscle stem cells. In 2015, after becoming an Associate Professor, he moved his laboratory to the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at the University of California San Francisco (UCSF). Dr. Brack is an Associate Professor, and Chair of Research in Orthopaedic Surgery. His current work focuses on three main areas:
1. Muscle stem cell heterogeneity to identify stress-resistant muscle stem cells.
2. The role of the niche in stem cell quiescence and activation during regeneration and aging.
3. Cell imaging and machine learning to identify predictors of stem cell aging and rejuvenation.