Neil Harris


Quach M, Ali I, Shultz SR, Casillas-Espinosa PM, Hudson MR, Jones NC, Silva JC, Yamakawa GR, Braine EL, Immonen R, Staba RJ, Tohka J, Harris NG, Gröhn O, O'Brien TJ, Wright DK. ComBating inter-site differences in field strength: harmonizing preclinical traumatic brain injury MRI data. NMR Biomed. 2024 Mar 18; e5142. view on PubMed

Ndode-Ekane XE, Ali I, Santana-Gomez C, Andrade P, Immonen R, Casillas-Espinosa P, Paananen T, Manninen E, Puhakka N, Smith G, Brady RD, Silva J, Braine E, Hudson M, Yamakawa GR, Jones NC, Shultz SR, Harris N, Wright DK, Gröhn O, Staba R, O'Brien TJ, Pitkänen A. Epilepsy phenotype and its reproducibility after lateral fluid percussion-induced traumatic brain injury in rats: Multicenter EpiBioS4Rx study project 1. Epilepsia. 2024 Feb; 65(2):511-526. view on PubMed

Ndode-Ekane XE, Ali I, Santana-Gomez CE, Casillas-Espinosa PM, Andrade P, Smith G, Paananen T, Manninen E, Immonen R, Puhakka N, Ciszek R, Hämäläinen E, Brady RD, Silva J, Braine E, Hudson MR, Yamakawa G, Jones NC, Shultz SR, Wright D, Harris N, Gröhn O, Staba RJ, O'Brien TJ, Pitkänen A. Successful harmonization in EpiBioS4Rx biomarker study on post-traumatic epilepsy paves the way towards powered preclinical multicenter studies. Epilepsy Res. 2024 Jan; 199:107263. view on PubMed

Smith G, Thapak P, Paydar A, Ying Z, Gomez-Pinilla F, Harris NG. Altering the Trajectory of Perfusion-Diffusion Deficits Using A BDNF Mimetic Acutely After TBI is Associated with Improved Functional Connectivity. Prog Neurobiol (Dover). 2023; 10(1). view on PubMed

Bhagavatula S, Cabeen R, Harris NG, Gröhn O, Wright DK, Garner R, Bennett A, Alba C, Martinez A, Ndode-Ekane XE, Andrade P, Paananen T, Ciszek R, Immonen R, Manninen E, Puhakka N, Tohka J, Heiskanen M, Ali I, Shultz SR, Casillas-Espinosa PM, Yamakawa GR, Jones NC, Hudson MR, Silva JC, Braine EL, Brady RD, Santana-Gomez CE, Smith GD, Staba R, O'Brien TJ, Pitkänen A, Duncan D, EpiBioS4Rx investigators. Image data harmonization tools for the analysis of post-traumatic epilepsy development in preclinical multisite MRI studies. Epilepsy Res. 2023 09; 195:107201. view on PubMed

Thapak P, Smith G, Ying Z, Paydar A, Harris N, Gomez-Pinilla F. The BDNF mimetic R-13 attenuates TBI pathogenesis using TrkB-related pathways and bioenergetics. Biochim Biophys Acta Mol Basis Dis. 2023 10; 1869(7):166781. view on PubMed

Paydar A, Harris NG. The pericontused cortex can support function early after TBI but it remains functionally isolated from normal afferent input. Exp Neurol. 2023 01; 359:114260. view on PubMed

van Vliet EA, Immonen R, Prager O, Friedman A, Bankstahl JP, Wright DK, O'Brien TJ, Potschka H, Gröhn O, Harris NG. A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3-WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force. Epilepsia Open. 2022 Aug 13. view on PubMed

Hubbard WB, Spry ML, Gooch JL, Cloud AL, Vekaria HJ, Burden S, Powell DK, Berkowitz BA, Geldenhuys WJ, Harris NG, Sullivan PG. Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury. Brain. 2021 12 31; 144(12):3788-3807. view on PubMed

Choe KY, Bethlehem RAI, Safrin M, Dong H, Salman E, Li Y, Grinevich V, Golshani P, DeNardo LA, Peñagarikano O, Harris NG, Geschwind DH. Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse. Neuron. 2022 03 02; 110(5):795-808.e6. view on PubMed

Motanis H, Khorasani LN, Giza CC, Harris NG. Peering into the Brain through the Retrosplenial Cortex to Assess Cognitive Function of the Injured Brain. Neurotrauma Rep. 2021; 2(1):564-580. view on PubMed

Li L, He L, Harris N, Zhou Y, Engel J, Bragin A. Topographical reorganization of brain functional connectivity during an early period of epileptogenesis. Epilepsia. 2021 05; 62(5):1231-1243. view on PubMed

LaPlaca MC, Huie JR, Alam HB, Bachstetter AD, Bayir H, Bellgowan PF, Cummings D, Dixon CE, Ferguson AR, Ferland-Beckham C, Floyd CL, Friess SH, Galanopoulou AS, Hall ED, Harris NG, Hawkins BE, Hicks RR, Hulbert LE, Johnson VE, Kabitzke PA, Lafrenaye AD, Lemmon VP, Lifshitz CW, Lifshitz J, Loane DJ, Misquitta L, Nikolian VC, Noble-Haeusslein LJ, Smith DH, Taylor-Burds C, Umoh N, Vovk O, Williams AM, Young M, Zai LJ. Pre-Clinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases. J Neurotrauma. 2021 05 15; 38(10):1399-1410. view on PubMed

Beitchman JA, Lifshitz J, Harris NG, Thomas TC, Lafrenaye AD, Hånell A, Dixon CE, Povlishock JT, Rowe RK. Spatial Distribution of Neuropathology and Neuroinflammation Elucidate the Biomechanics of Fluid Percussion Injury. Neurotrauma Rep. 2021; 2(1):59-75. view on PubMed

Atkinson KC, Lee JB, Hasselmann JPC, Kim SH, Drew A, Soto J, Katzenellenbogen JA, Harris NG, Obenaus A, Tiwari-Woodruff SK. Diffusion tensor imaging identifies aspects of therapeutic estrogen receptor β ligand-induced remyelination in a mouse model of multiple sclerosis. Neurobiol Dis. 2019 10; 130:104501. view on PubMed

Sta Maria NS, Sargolzaei S, Prins ML, Dennis EL, Asarnow RF, Hovda DA, Harris NG, Giza CC. Bridging the gap: Mechanisms of plasticity and repair after pediatric TBI. Exp Neurol. 2019 08; 318:78-91. view on PubMed

Ringler E, Coates M, Cobo-Cuan A, Harris NG, Narins PM. MEMRI for visualizing brain activity after auditory stimulation in frogs. Behav Neurosci. 2019 Jun; 133(3):329-340. view on PubMed

Immonen R, Smith G, Brady RD, Wright D, Johnston L, Harris NG, Manninen E, Salo R, Branch C, Duncan D, Cabeen R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Shultz SR, Andrade P, Puhakka N, Staba RJ, O'Brien TJ, Toga AW, Pitkänen A, Gröhn O. Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis. Epilepsy Res. 2019 02; 150:46-57. view on PubMed

Immonen R, Harris NG, Wright D, Johnston L, Manninen E, Smith G, Paydar A, Branch C, Grohn O. Imaging biomarkers of epileptogenecity after traumatic brain injury - Preclinical frontiers. Neurobiol Dis. 2019 03; 123:75-85. view on PubMed

Verley DR, Torolira D, Hessell BA, Sutton RL, Harris NG. Cortical Neuromodulation of Remote Regions after Experimental Traumatic Brain Injury Normalizes Forelimb Function but is Temporally Dependent. J Neurotrauma. 2019 03 01; 36(5):789-801. view on PubMed

McDonald WS, Jones EE, Wojciak JM, Drake RR, Sabbadini RA, Harris NG. Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology. Am J Pathol. 2018 08; 188(8):1779-1793. view on PubMed

Verley DR, Torolira D, Pulido B, Gutman B, Bragin A, Mayer A, Harris NG. Remote Changes in Cortical Excitability after Experimental Traumatic Brain Injury and Functional Reorganization. J Neurotrauma. 2018 10 15; 35(20):2448-2461. view on PubMed

Sargolzaei S, Cai Y, Wolahan SM, Gaonkar B, Sargolzaei A, Giza CC, Harris NG. A Comparative Study of Automatic Approaches for Preclinical MRI-based Brain Segmentation in the Developing Rat. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:652-655. view on PubMed

Paulson C, Chien D, Lin F, Seidlits S, Cai Y, Sargolzaei S, Harris NG, Giza CC. A Novel Modular Headmount Design for non-invasive Scalp EEG Recordings in Awake Animal Models. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:5422-5425. view on PubMed

Sargolzaei S, Cai Y, Walker MJ, Hovda DA, Harris NG, Giza CC. Craniectomy Effects on Resting State Functional Connectivity and Cognitive Performance in Immature Rats. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:5414-5417. view on PubMed

Sargolzaei S, Cai Y, Lee D, Harris NG, Giza CC. Quantification of Biological Responses as Predictors of Cognitive Outcome after Developmental TBI. IEEE EMBS Int Conf Biomed Health Inform. 2018 Mar; 2018:381-384. view on PubMed

Choe KY, Sanchez CF, Harris NG, Otis TS, Mathews PJ. Optogenetic fMRI and electrophysiological identification of region-specific connectivity between the cerebellar cortex and forebrain. Neuroimage. 2018 06; 173:370-383. view on PubMed

Krishna G, Agrawal R, Zhuang Y, Ying Z, Paydar A, Harris NG, Royes LFF, Gomez-Pinilla F. 7,8-Dihydroxyflavone facilitates the action exercise to restore plasticity and functionality: Implications for early brain trauma recovery. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1204-1213. view on PubMed

Sta Maria NS, Reger ML, Cai Y, Baquing MAT, Buen F, Ponnaluri A, Hovda DA, Harris NG, Giza CC. D-Cycloserine Restores Experience-Dependent Neuroplasticity after Traumatic Brain Injury in the Developing Rat Brain. J Neurotrauma. 2017 04 15; 34(8):1692-1702. view on PubMed

Shijo K, Sutton RL, Ghavim SS, Harris NG, Bartnik-Olson BL. Metabolic fate of glucose in rats with traumatic brain injury and pyruvate or glucose treatments: A NMR spectroscopy study. Neurochem Int. 2017 01; 102:66-78. view on PubMed

Molet J, Maras PM, Kinney-Lang E, Harris NG, Rashid F, Ivy AS, Solodkin A, Obenaus A, Baram TZ. MRI uncovers disrupted hippocampal microstructure that underlies memory impairments after early-life adversity. Hippocampus. 2016 12; 26(12):1618-1632. view on PubMed

Brown RJ, Jun BJ, Cushman JD, Nguyen C, Beighley AH, Blanchard J, Iwamoto K, Schaue D, Harris NG, Jentsch JD, Bluml S, McBride WH. Changes in Imaging and Cognition in Juvenile Rats After Whole-Brain Irradiation. Int J Radiat Oncol Biol Phys. 2016 10 01; 96(2):470-478. view on PubMed

Moro N, Ghavim SS, Harris NG, Hovda DA, Sutton RL. Pyruvate treatment attenuates cerebral metabolic depression and neuronal loss after experimental traumatic brain injury. Brain Res. 2016 07 01; 1642:270-277. view on PubMed

Harris NG, Verley DR, Gutman BA, Sutton RL. Bi-directional changes in fractional anisotropy after experiment TBI: Disorganization and reorganization? Neuroimage. 2016 06; 133:129-143. view on PubMed

Harris NG, Verley DR, Gutman BA, Thompson PM, Yeh HJ, Brown JA. Disconnection and hyper-connectivity underlie reorganization after TBI: A rodent functional connectomic analysis. Exp Neurol. 2016 Mar; 277:124-138. view on PubMed

Shijo K, Ghavim S, Harris NG, Hovda DA, Sutton RL. Glucose administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral and histological outcomes. Brain Res. 2015 Jul 21; 1614:94-104. view on PubMed

Thomsen GM, Le Belle JE, Harnisch JA, Mc Donald WS, Hovda DA, Sofroniew MV, Kornblum HI, Harris NG. Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone. Stem Cell Res. 2014 Jul; 13(1):48-60. view on PubMed

Bartnik-Olson BL, Harris NG, Shijo K, Sutton RL. Insights into the metabolic response to traumatic brain injury as revealed by (13)C NMR spectroscopy. Front Neuroenergetics. 2013 Oct 04; 5:8. view on PubMed

Moro N, Ghavim S, Harris NG, Hovda DA, Sutton RL. Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury. Brain Res. 2013 Oct 16; 1535:124-36. view on PubMed

Harris NG, Nogueira MS, Verley DR, Sutton RL. Chondroitinase enhances cortical map plasticity and increases functionally active sprouting axons after brain injury. J Neurotrauma. 2013 Jul 15; 30(14):1257-69. view on PubMed

Harris NG, Chen SF, Pickard JD. Cortical reorganization after experimental traumatic brain injury: a functional autoradiography study. J Neurotrauma. 2013 Jul 01; 30(13):1137-46. view on PubMed

Harris NG, Mironova YA, Chen SF, Richards HK, Pickard JD. Preventing flow-metabolism uncoupling acutely reduces axonal injury after traumatic brain injury. J Neurotrauma. 2012 May 01; 29(7):1469-82. view on PubMed

Deng-Bryant Y, Prins ML, Hovda DA, Harris NG. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. J Neurotrauma. 2011 Sep; 28(9):1813-25. view on PubMed

Harris NG, Mironova YA, Hovda DA, Sutton RL. Chondroitinase ABC enhances pericontusion axonal sprouting but does not confer robust improvements in behavioral recovery. J Neurotrauma. 2010 Nov; 27(11):1971-82. view on PubMed

Duxbury JA, Wright KM, Hart A, Bradley D, Roach P, Harris N, Carter B. A structured observation of the interaction between nurses and patients during the administration of medication in an acute mental health unit. J Clin Nurs. 2010 Sep; 19(17-18):2481-92. view on PubMed

Harris NG, Mironova YA, Hovda DA, Sutton RL. Pericontusion axon sprouting is spatially and temporally consistent with a growth-permissive environment after traumatic brain injury. J Neuropathol Exp Neurol. 2010 Feb; 69(2):139-54. view on PubMed

Harris NG, Carmichael ST, Hovda DA, Sutton RL. Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited. J Neurosci Res. 2009 Oct; 87(13):2937-50. view on PubMed

Giza CC, Kolb B, Harris NG, Asarnow RF, Prins ML. Hitting a moving target: Basic mechanisms of recovery from acquired developmental brain injury. Dev Neurorehabil. 2009; 12(5):255-68. view on PubMed

Baker JA, Lovell K, Harris N. A best-evidence synthesis review of the administration of psychotropic pro re nata (PRN) medication in in-patient mental health settings. J Clin Nurs. 2008 May; 17(9):1122-31. view on PubMed

Smith JM, Lunga P, Story D, Harris N, Le Belle J, James MF, Pickard JD, Fawcett JW. Inosine promotes recovery of skilled motor function in a model of focal brain injury. Brain. 2007 Apr; 130(Pt 4):915-25. view on PubMed

Ben Simon GJ, Hovda DA, Harris NG, Gomez-Pinilla F, Goldberg RA. Traumatic brain injury induced neuroprotection of retinal ganglion cells to optic nerve crush. J Neurotrauma. 2006 Jul; 23(7):1072-82. view on PubMed

King MD, Crowder MJ, Hand DJ, Harris NG, Williams SR, Obrenovitch TP, Gadian DG. Is anoxic depolarisation associated with an ADC threshold? A Markov chain Monte Carlo analysis. NMR Biomed. 2005 Dec; 18(8):587-94. view on PubMed

Bartnik BL, Sutton RL, Fukushima M, Harris NG, Hovda DA, Lee SM. Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. J Neurotrauma. 2005 Oct; 22(10):1052-65. view on PubMed

Johnström P, Fryer TD, Richards HK, Harris NG, Barret O, Clark JC, Pickard JD, Davenport AP. Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo. Br J Pharmacol. 2005 Jan; 144(1):115-22. view on PubMed

Chen SF, Richards HK, Smielewski P, Johnström P, Salvador R, Pickard JD, Harris NG. Relationship between flow-metabolism uncoupling and evolving axonal injury after experimental traumatic brain injury. J Cereb Blood Flow Metab. 2004 Sep; 24(9):1025-36. view on PubMed

Owler BK, Pena A, Momjian S, Czosnyka Z, Czosnyka M, Harris NG, Smielewski P, Fryer T, Donvan T, Carpenter A, Pickard JD. Changes in cerebral blood flow during cerebrospinal fluid pressure manipulation in patients with normal pressure hydrocephalus: a methodological study. J Cereb Blood Flow Metab. 2004 May; 24(5):579-87. view on PubMed

Owler BK, Momjian S, Czosnyka Z, Czosnyka M, Péna A, Harris NG, Smielewski P, Fryer T, Donovan T, Coles J, Carpenter A, Pickard JD. Normal pressure hydrocephalus and cerebral blood flow: a PET study of baseline values. J Cereb Blood Flow Metab. 2004 Jan; 24(1):17-23. view on PubMed

King MD, Crowder MJ, Hand DJ, Harris NG, Williams SR, Obrenovitch TP, Gadian DG. Temporal relation between the ADC and DC potential responses to transient focal ischemia in the rat: a Markov chain Monte Carlo simulation analysis. J Cereb Blood Flow Metab. 2003 Jun; 23(6):677-88. view on PubMed

Lythgoe MF, Sibson NR, Harris NG. Neuroimaging of animal models of brain disease. Br Med Bull. 2003; 65:235-57. view on PubMed

Harris NG, Gauden V, Fraser PA, Williams SR, Parker GJ. MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemia. Magn Reson Imaging. 2002 Apr; 20(3):221-30. view on PubMed