D’Juan Farmer*

/in /by

D’Juan Farmer, Ph.D.

Office Address:
BSRB 547

Affiliations

Assistant Professor, Molecular, Cell and Developmental Biologyy
Research Interests

In the Farmer lab, we aim to decipher the inter-cellular and intra-cellular mechanisms that drive craniofacial development. We investigate the tissue interactions and gene regulatory networks that establish and maintain skeletal progenitors during embryonic and postnatal development. By dissecting the mechanisms that control craniofacial development, we hope to inform new therapies and interventions that improve outcomes for patients with craniofacial anomalies.

Publications

A selected list of publications:

Ting MC, Farmer DT, Teng CS, Crump JG. 2021. Maxson RE. Embryonic requirements of Tcf12 for development of the mouse coronal suture. Development. doi: 10.1242/dev.199575.

Farmer DT, Mlcochov, H, Zhou Y, Koelling N, Wang G, Ashley N, Bugacov H, Chen HJ, Parvez R, Tseng KC, Merrill A, Maxson RE, Crump JG, Wilie AOM. 2021. The developing mouse coronal suture at single-cell resolution. Nature Communications. https://doi.org/10.1038/s41467-021-24917-9.

Farmer DT, Patel P, Choi R, Liu CY, Crump JG. 2021. Widespread roles for Irx proteins in formation and individuation of cartilages in the facial and appendicular skeletons. Development. dev.197244. doi: 10.1242/dev.197244

Giovannone D, Paul S, Schindler S, Arata C, Farmer DT, Patel P, Smeeton J, Crump JG. 2019. Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones. pii: e42736. doi: 10.7554/eLife.42736.

Teng CS, Ting MC, Farmer DT, Brockop M, Maxson RE, Crump JG. 2018. Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. pii: e37024. doi: 10.7554/eLife.37024.

Farmer DT, Nathan S, Shengyang K, Emmerson E, Finely J, Byrnes L, Sneddon J, McManus MT, Tward A, Knox SM. 2017. Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Development. pii: dev.150789. doi: 10.1242/dev.150789.

Farmer DT, Finley JK, Chen FY, Tarifeño-Saldivia E, Knox SM, McNamara N, McManus MT. 2017. miR-205 is a critical regulator of lacrimal gland development. Dev Biol. pii: S0012-1606(17)30201-4. doi: 10.1016/j.ydbio.2017.05.012.

Farmer DT, McManus MT. 2017. MicroRNAs in ectodermal appendages. Curr Opin Genet Dev. 16;43:61-66. doi: 10.1016/j.gde.2016.12.006

Finley JK, Farmer D, Emmerson E, Cruz Pacheco N, Knox SM. 2014. Manipulating the Murine Lacrimal Gland. J. Vis. Exp. 201:93, e51970. doi: 10.3791/51970.

Farmer DT, Shariat N, Park CY, Liu HJ, Mavropoulos A, McManus MT. 2013. Partially Penetrant Postnatal Lethality of an Epithelial Specific MicroRNA in a Mouse Knockout. PLoS ONE 8:10, e76634. doi: 10.1371/journal.pone.0076634