Immunity, Microbes, and Molecular Pathogenesis


The Immunity, Microbes & Molecular Pathogenesis (IMMP) Home Area offers students an inspired training program that focuses on the study of microbes and the immune system that defends against microbes as well as other diseases. The IMMP Home Area is a community of over 60 faculty members with expertise in immunology, microbial pathogenesis, and microbial physiology. The immunology group studies the innate and adaptive immune response and seeks to exploit the immune system to discover new therapies for a wide array of diseases from infections to immune-mediated disorders and cancer. The microbial pathogenesis group specializes in revealing the molecular mechanisms of microbial pathogenesis and host-pathogen interactions for a broad variety of viruses, bacteria and parasites that cause substantial morbidity and mortality worldwide. The microbial physiologists study the metabolic and regulatory networks of microbes and determine how their diverse and often extreme environmental adaptations result in unique biological systems and provide opportunities for novel metabolic engineering. Collectively, the IMMP laboratories use multidisciplinary approaches including microbial genetics, molecular imaging, structural biology, transgenic animals, and genomics/proteomics to understand basic biological mechanisms and then use this knowledge to combat human infections and diseases. The UCLA resources utilized by our faculty include BSL3 facilities, the Molecular Screening Shared Resource (MSSR), the Jonsson Comprehensive Cancer Center, the Electron Imaging Center for Nanomachines, the Crump Institute for Molecular Imaging, and the Ahmanson Biological Imaging Center. We provide a rigorous and enthusiastic training program that enables our students to make a direct impact on human health and the environment and prepares students for successful careers as research scientists in top academic institutions, biotechnology industries, and government agencies.



I3T Seminar Speaker
Date & Time: Mar 14, 2017 12:00 PM – 1:00 PM Location: 23-105 CHS

Metabolic Control of Macrophage Activation

Tiffany Horng, Ph.D.
Associate Professor
Department of Genetics and Complex Diseases
Department of Immunology and Infectious Diseases
Harvard School of Public Health

Light Lunch Will Be Provided

Sponsored by the David Geffen School of Medicine Initiative in Immunity, Inflammation, Infection, and Transplantation (I3T)


UCLA Otto Yang research suggests that a gene-based immunotherapy has shown promissing results against cancer could as be used against HIV.

The use of these chimeric receptors is currently the focus of gene immunotherapy against cancer, but they could also be used to create a strong immune response against HIV, said Dr. Otto Yang, professor of medicine in the division of infectious diseases at the David Geffen School of Medicine at UCLA…  Read more here

Home Area Director

PBradley_croppedPeter Bradley, Ph.D
2610B MSB