Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. Qi J, Lee HJ, Saquet A, Cheng XN, Shao M, Zheng JJ, Shi DL. J Biol Chem. 2017 Apr 7;292(14):5898-5908.
Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01. Vöpel T, Bravo-Rodriguez K, Mittal S, Vachharajani S, Gnutt D, Sharma A, Steinhof A, Fatoba O, Ellrichmann G, Nshanian M, Heid C, Loo JA, Klärner FG, Schrader T, Bitan G, Wanker EE, Ebbinghaus S, Sanchez-Garcia E. J Am Chem Soc. 2017 Apr 26;139(16):5640-5643.
There are no upcoming events at this time.
MBI Thursday Seminars have concluded for this academic year and will resume Fall 2017.
Thank you for your participation!