Jessica Ong

Jessica Ong

Home Area: Cell and Developmental Biology
Mentor: Karen Reue
Research project:

Jessica is examining the physiological roles of a protein called Diet1 in the mouse model organism. A lack of Diet1 has previously been shown to make mice less susceptible to hypercholesterolemia when put on an atherogenic diet due to an enhanced bile acid secretion phenotype.

Publications:

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants. Lee, J. M.*, Ong, J. R.*, Vergnes, L., de Aguiar Vallim, T. Q., Nolan, J., Cantor, R. M., Walters, J. R. F., and Reue, K. Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants. Lipid Res. (2018); 59(3):429-438.

Hmga2 is dispensable for cutaneous squamous cell carcinoma. White A, Flores A, Ong J, Lowry WE. Exp Dermatol. 2016 May;25(5):409-12. doi: 10.1111/exd.12978