Andrew Hildreth

/in /by
Research project:

Andrew’s research involves the dissecting IL-12 regulatory networks and the roles of cDC1 in regulating immune responses in Type II Diabetes and Cancer.

Publications:
CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Mature Primary Innate Immune – Hildreth, A.D.*, Riggan, L.*, Rolot, M., Wong, Y. Satyadi, W., Sun, R., Huerta, C, and. O’Sullivan,
T.E. Cells. Cell Rep. 31, 107651 (2020). (*co-first author)
Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes – Nabekura, T., Riggan, L., Hildreth, A. D., O’Sullivan, T. E. & Shibuya, A. Immunity 52, 96-108.e9 (2020).
Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains – Fields, F., Freed, S., Carothers, K., Hamid, Md N., Hammers, D., Ross, J., Kalwajtys, V., Gonzalez, A., Hildreth, A., Friedberg, I., Lee, S. Drug Dev. Res. ddr.21601 (2019).

Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection – Hildreth A,  and O’Sullivan, T. Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection. Viruses. 2019; 11(3), 272. doi: 10.3390/v11030272

Mouse cytomegalovirus-experienced ILC1S acquire a memory response dependent on the viral glycoprotein m12 – Weizman OE, Song E, Adams NM, Hildreth AD, Riggan L, Krishna C, Aguilar OA, Leslie CS Carlyle JR, Sun JC & O’Sullivan TE. Mouse cytomegalovirus-experienced ILC1S acquire a memory response dependent on the viral glycoprotein m12. Nature Immunology. 2019. doi: 10.1038/s41590-019-0430-1