MBIDP Student Defense - Jessica M. Ochoa
2021-05-28 12:00 - 14:00 (America/Los_Angeles) | Zoom

MBI Thursday Research Seminar | Crystal Rogers, Ph.D. | Hosted by Siobhan Braybrook
2021-05-27 09:00 - 10:00 | Zoom
“Regulating cell fate and survival during embryonic development”
Crystal Rogers, Ph.D.
Assistant Professor, Anatomy, Physiology and Cell Biology
School of Veterinary Medicine
University of California, Davis

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

MBI Faculty Seminar - Sophie Deng, M.D., Ph.D.
2021-05-25 12:00 - 13:00 | Zoom
Sophie Deng, M.D., Ph.D.
Professor, Ophthalmology

All MBI Faculty Welcome

MBI Thursday Research Seminar | Melina Schuh, Ph.D. | Hosted by Margot Quinlan
2021-05-20 09:00 - 10:00 | Zoom
“New insights into aneuploidy in mammalian embryos”
Melina Schuh, Ph.D.
Director, Department of Meiosis
Max Planck Institute for Biophysical Chemistry
Abstract: The Schuh lab studies meiosis in mammalian oocytes. In her presentation, Melina will summarize her lab’s recent research on the spindle in mammalian oocytes. Her lab found that human oocyte spindles are surprisingly unstable, and identified functions for actin and a liquid-like meiotic spindle domain for spindle assembly in mammalian oocytes.
In the main part of her talk, she will present recent work from her lab that sheds light on the origin of high aneuploidy rates in mammalian embryos. The vast majority of human embryos are aneuploid. Aneuploidy frequently arises during the early mitotic divisions of the embryo, but the origin of this remains elusive. Using bovine embryos as a model for human embryos, we identify an error-prone mechanism of parental genome unification which often results in aneuploidy. Surprisingly, genome unification initiates hours before breakdown of the two pronuclei that encapsulate the parental genomes. While still within intact pronuclei, the parental genomes polarize towards each other, in a process driven by centrosomes, dynein, and microtubules. The maternal and paternal chromosomes eventually cluster at the pronuclear interface, in direct proximity to each other. Parental genome clustering often fails however, leading to severe chromosome segregation errors, incompatible with healthy embryo development. Nucleoli, which associate with chromatin, also cluster at the pronuclear interface in human zygotes. Defects in nucleolar clustering correlate with failure in human embryo development, suggesting a conserved mechanism.

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

MBI Thursday Research Seminar | Sarah Slavoff, Ph.D. | Hosted by Keriann Backus
2021-05-13 09:00 - 10:00 | Zoom
“Dark Matter of the Human Genome: Small Open Reading Frames”
Sarah Slavoff, Ph.D.
Assistant Professor of Chemistry and of Molecular Biophysics and Biochemistry
Yale University

MBI Faculty Seminar - William Gelbart, Ph.D.
2021-05-11 12:00 - 13:00 | Zoom
William Gelbart, Ph.D.
Distinguished Professor, Chemistry & Biochemistry

All MBI Faculty Welcome

MBI Thursday Research Seminar | Sarah Teichmann, FMedSci FRS | Hosted by Maureen Su
2021-05-06 09:00 - 10:00 | Zoom
“Mapping the human intestines throughout life: one cell at a time”
Sarah Teichmann, FMedSci FRS
Head of Cellular Genetics
Wellcome Sanger Institute

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

UCLA Joint Seminars in Neuroscience Lecture | Liqun Luo, Ph.D. | Hosted by Weizhe Hong and Orkun Akin
2021-05-04 12:00 - 13:00 | Zoom
“Wiring Specificity of Neural Circuits”
Liqun Luo, Ph.D.
Ann & Bill Swindells Professor
Departtment of Biology, Stanford University
Investigator, Howard Hughes Medical Institute

MBI Thursday Research Seminar | Shawn Burgess, Ph.D. | Hosted by Marc Liesa-Roig
2021-04-29 09:00 - 10:00 | Zoom
“Mapping Mitochondrial Metabolism in Liver and its Importance in NAFLD”
Shawn Burgess, Ph.D.
Professor, Human Nutrition, Pharmacology
The University of Texas Southwestern Medical Center

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

MBI Thursday Research Seminar | Bil Clemons, Ph.D. | Hosted by Jose Rodriguez and Tracy Johnson
2021-04-22 09:00 - 10:00 | Zoom
“A detailed look at tail-anchored membrane protein targeting – from opisthokonts to protists to plants”
Bil Clemons, Ph.D.
Professor, Biochemistry
California Institute of Technology

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

2020-2021 Sigman Symposium
2021-04-15 10:00 - 11:45 | Zoom
Sigman Symposium Schedule
Sigman Symposium Poster Session

MBI Thursday Research Seminar | Clifford Brangwynne, Ph.D. | Hosted by Margot Quinlan and Kathrin Plath
2021-04-08 09:00 - 10:00 | Zoom
“Fluid forces – phase separation in, on, and around the genome”
Clifford Brangwynne, Ph.D.
Director, Princeton Bioengineering Initiative
June K. Wu ’92 Professor in Engineering
Professor of Chemical and Biological Engineering
Princeton University

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

MBI Faculty Seminar - Aparna Bhaduri, Ph.D.
2021-04-06 12:00 - 13:00
“An Atlas of Cortical Arealization Identifies Dynamic Molecular Signatures”
Aparna Bhaduri, Ph.D.
Assistant Professor, Biological Chemistry

All MBI Faculty Welcome

MBI Thursday Research Seminar | Sabine Petry, Ph.D. | Hosted by Margot Quinlan
2021-04-01 09:00 - 10:00 | Zoom
“How to make microtubules and build the cytoskeleton”
Sabine Petry, Ph.D.
Associate Professor, Molecular Biology
Princeton University
Abstract:
How does a cell construct its microtubule cytoskeleton? According to Feynman’s principle “what I cannot create, I do not understand”, my lab pursues this question by building the chromosome segregation machinery from scratch. I will first tell you how the microtubule framework is generated in a cell. Upon deciphering the function of the most important microtubule accessory proteins, I will present how we use those building blocks to reconstitute a spindle substructure in vitro and determine its building plan. Finally, I will outline how we combine spindle substructures like pieces of a puzzle to assemble and thereby understand a functioning spindle that segregates chromosomes.
By studying how the MT cytoskeleton is built, I hope to help explain how hundreds of proteins can self-assemble on the nm scale into a complex molecular machine 1000-fold larger than its constituents, a challenge for the biochemistry of the 21st century

Please email mbiasst@lifesci.ucla.edu to request Zoom link.

Journey Talk - Elizabeth Zuniga-Sanchez, Ph.D.
2021-03-31 13:00 - 14:00 | Zoom
“Unraveling the molecular code in neural circuit assembly”
Elizabeth Zuniga-Sanchez, Ph.D.
Assistant Professor, Ophthalmology
Baylor College of Medicine

MB-IDP Town Hall
2020-06-15 14:00 - 15:00
For Zoom details please email mbigrad@lifesci.ucla.edu

MBIDP Student Seminar
2020-06-11 11:00 - 12:00
Amara Thind (Bradley Lab)
“Discovery and Characterization of Novel Bradyzoite Dense Granule Proteins in Toxoplasma gondii.”
Please contact mbigrad@lifesci.ucla.edu for Zoom details.

MBIDP Short Talks Round 2
2020-06-04 16:00 - 17:00
Matt Lowe “Functional Artwork: How to Start a Record Collection”
Matilde Miranda “Skincare Bootcamp”
Lauren Thurlow “Infinite Houseplants”
Andrew Lopez “Film Cameras 101”

Please email mbigrad@lifesci.ucla.edu for Zoom information

Thursday Research Seminar Series
2020-05-28 16:00 - 17:00
Russell Vance, Ph.D.
Professor, Molecular & Cell Biology
UC, Berkeley
More information coming soon!

Baking with the BEST
2020-05-27 19:00 - 20:00
Featuring: Ian Ford, Michal Juda, and Kaiser Atai

Defense: Cynthia Shu
2020-05-22 14:00 - 16:00
“Discovery and development of small molecule sarcospan enhancers for the treatment of Duchenne muscular dystrophy”
Mentor: Rachelle Crosbie-Watson

Zoom location: https://uconline.zoom.us/j/235712900
Please email mbigrad@lifesci.ucla.edu for password

MBIDP Student Seminar
2020-05-20 13:30 - 14:00
Feiyang Ma (Pellegrini Lab)

MBIDP Talk
2020-05-07 17:00 - 18:00
“Organizing work at home: Lessons from ADD/ADHD”
by Siobhan Braybrook

Mental Health Seminar
2020-05-06 14:00 - 15:00
“Combating isolation as a grad student”
w/ Fay Lin

Join via Zoom at: https://ucla.zoom.us/j/99392326644?pwd=[REDACTED]
Please email mbigrad@lifesci.ucla.edu for password

Jimmy Hu, Ph.D.
2020-05-05 12:00 - 13:00
“Regulation of adult mouse dental epithelial progenitor cells by YAP and tissue architecture”
All MBI Faculty Welcome
Zoom link: https://ucla.zoom.us/j/94027699869?pwd=[REDACTED]
Please email mbiasst@lifesci.ucla.edu for password

Defense: Ade Adelaja
2020-05-01 09:00 - 11:00
“Stimulus-specificity of NFκB signaling in macrophages”
Mentor: Alexander Hoffmann

MBIDP Student Seminar
2020-04-29 13:30 - 14:00
Eta Atolia (Butte Lab)
“Reverse engineering vaccine neoantigens”

MBIDP Student Seminar
2020-04-24 14:30 - 15:00
Tasha Lin (Rao Lab)

Zoom link: https://ucla.zoom.us/j/93530902154?pwd=[REDACTED]
Please email mbigrad@lifesci.ucla.edu for password

MBIDP Happy Hour
2020-04-23 16:00 - 17:00
MBIDP Happy Hour with Matilde Miranda ft. origami crafts
No origami paper? No problem. Most paper is fine!!
Zoom link: https://ucla.zoom.us/j/94507919934?pwd=[REDACTED]
Email mbigrad@lifesci.ucla.edu for password

Siobhan Braybrook, Ph.D.
2020-04-21 12:00 - 13:00
Siobhan Braybrook, Ph.D.
Assistant Professor, Molecular, Cell, and Developmental Biology

All MBI Faculty Welcome
Please email mbiasst@lifesci.ucla.edu for Zoom link and password.
