An-Chieh Feng

Research project:

An-Chieh researches epigenetic profiling of the inflammatory response regulation in macrophages.

Publications:

Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins – Zhou QD, Chi X, Lee MS, Hsieh WY, Mkrtchyan JJ, Feng AC, He C, York AG, Bui VL, Kronenberger EB, Ferrari A, Xiao X, Daly AE, Tarling EJ, Damoiseaux R, Scumpia PO, Smale ST, Williams KJ, Tontonoz P, Bensinger SJ. Nat Immunol. 2020 Jul;21(7):746-755.

Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice – Zhang Z, Feng AC, Salisbury D, Liu X, Wu X, Kim J, Lapina I, Wang D, Lee B, Fraga J, Pan C, Williams KJ, Lusis AJ, Scumpia P, Sallam T. Nat Commun. 2020 Feb 20;11(1):984.

Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes – Rajbhandari P, Arneson D, Hart SK, Ahn IS, Diamante G, Santos LC, Zaghari N, Feng AC, Thomas BJ, Vergnes L, Lee SD, Rajbhandari AK, Reue K, Smale ST, Yang X, Tontonoz P. Elife. 2019 Oct 23;8:e49501.

Enhanced In Vivo Delivery of Stem Cells using Microporous Annealed Particle Scaffolds – Koh J, Griffin DR, Archang MM, Feng AC, Horn T, Margolis M, Zalazar D, Segura T, Scumpia PO, Di Carlo D. Small. 2019 Sep;15(39):e1903147.

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure – Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, and Tontonoz P. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018; 172(1-2): 218-233.e17.

HCV core inhibits hepatocellular carcinoma replicative senescence through downregulating microRNA-138 expression – Shiu TY, Shih YL, Feng AC, Lin HH, Huang SM, Huang TY, Hsieh CB, Chang WK, Hsieh TY. HCV core inhibits hepatocellular carcinoma replicative senescence through downregulating microRNA-138 expression. J Mol Med (Berl). 2017;95(6):629-639.