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Wanlu Liu

Wanlu Liu

Home Area: Cell and Developmental Biology
Mentor: Steve Jacobsen
Research project:

Wanlu is interested in studying DNA methylation in the model plant Arabidopsis thaliana with next generation sequencing techniques.

Publications:

Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. Clark AT, Gkountela S, Chen D, Liu W, Sosa E, Sukhwani M, Hennebold JD, Orwig KE. Stem Cell Reports. 2017 Jul 11;9(1):329-341. doi: 10.1016/j.stemcr.2017.05.002. Epub 2017 Jun 1.

DNA methylome of the 20-gigabase Norway spruce genome. Ausin I, Feng S, Yu C, Liu W, Kuo HY, Jacobsen EL, Zhai J, Gallego-Bartolome J, Wang L, Egertsdotter U, Street NR, Jacobsen SE, Wang H. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8106-E8113. Epub 2016 Nov 28.

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. Li S, Yen L, Pastor WA, Johnston JB, Du J, Shew CJ, Liu W, Ho J, Stender B, Clark AT, Burlingame AL, Daxinger L, Patel DJ, Jacobsen SE. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5108-16. doi: 10.1073/pnas.1609709113. Epub 2016 Aug 15.

Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes. Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen SE. PLoS Genet. 2016 May 12;12(5):e1005998. doi: 10.1371/journal.pgen.1005998. eCollection 2016 May

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Pastor WA*, Chen D*, Liu W*, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. Cell Stem Cell. 2016 Mar 3;18(3):323-9. doi: 10.1016/j.stem.2016.01.019. Epub 2016 Feb 4.

A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis. Zhai J, Bischof S, Wang H, Feng S, Lee TF, Teng C, Chen X, Park SY, Liu L, Gallego-Bartolome J, Liu W, Henderson IR, Meyers BC, Ausin I, Jacobsen SE. Cell. 2015 Oct 8;163(2):445-55. doi: 10.1016/j.cell.2015.09.032.

MORC1 represses transposable elements in the mouse male germline. Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc’his D, Aravin AA, Clark AT, Jacobsen SE. Nat Commun. 2014 Dec 12;5:5795. doi: 10.1038/ncomms6795. Erratum in: Nat Commun. 2015;6:7604.