Home Area: Cell and Developmental Biology
Mentor: Kathrin Plath and Amander Clark
Tsotne’s research focuses on Long non-coding RNA, XIST mediated molecular mechanisms of X chromosome regulation in human embryonic development. We study this epigenetic event in human pluripotent stem cells and human primordial germ cells.
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency – Yu Tao, Ming-Ren Yen, Tsotne Chitiashvili, Haruko Nakano, Rachel Kim, Linzi Hosohama, Yao Chang Tan, Atsushi Nakano, Pao-Yang Chen & Amander T. Clark. Stem Cell Reports 2017 doi:10.1016/j.stemcr.2017.11.020
Boehringer Ingelheim PhD Fellowship: https://www.bifonds.de/fellowships-grants/phd-fellowships.html