Peter Back
Peter Back studies the composition and function of the inner membrane complex (IMC) of the opportunistic pathogen Toxoplasma gondii.
Publications:
Choi CP, Moon AS, Back PS, Jami-Alahmadi Y, Vashisht AA, Wohlschlegel JA, Bradley PJ. A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex. PLoS Biol. 2019 Oct 4;17(10):e3000475. doi: 10.1371/journal.pbio.3000475.
Back PS*, O’Shaughnessy WJ*, Moon AS, Dewangan PS, Hu X, Sha J, Wohlschlegel JA, Bradley PJ+, Reese ML+. Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis. Proc Natl Acad Sci USA. 2020 Jun 2;117(22):12164-12173. doi: 10.1073/pnas.1921245117.
Torres JA, Pasquarelli RR, Back PS, Moon AS, Bradley PJ. Identification and Molecular Dissection of IMC32, a Conserved Toxoplasma Inner Membrane Complex Protein That Is Essential for Parasite Replication. mBio. 2021 Feb 16;12(1):e03622-20. doi: 10.1128/mBio.03622-20.
Back PS*, O’Shaughnessy WJ*, Moon AS, Dewangan PS, Reese ML+, Bradley PJ+. Multivalent Interactions Drive the Toxoplasma AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap. mBio. 2022 Feb 8;13(1):e0286421. doi: 10.1128/mbio.02864-21.
