Jessica is examining the physiological roles of a protein called Diet1 in the mouse model organism. A lack of Diet1 has previously been shown to make mice less susceptible to hypercholesterolemia when put on an atherogenic diet due to an enhanced bile acid secretion phenotype.
Hmga2 is dispensable for cutaneous squamous cell carcinoma. White A, Flores A, Ong J, Lowry WE. Exp Dermatol. 2016 May;25(5):409-12. doi: 10.1111/exd.12978