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Aimee Flores

Aimee Flores

Home Area: Cell and Developmental Biology
Mentor: Bill Lowry
Research project:

Using the hair follicle as a model system for tumorigenesis with a stem cell origin, Aimee is exploring the role of metabolism in tissue homeostasis and tumor intitiation by hair follicle stem cells.

Publications:

Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma. Lowry WE, Flores A, White AC. J Invest Dermatol. 2016 May 7. pii: S0022-202X(16)30978-2. doi: 10.1016/j.jid.2016.03.017. [Epub ahead of print] Review.

Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell-induced squamous cell carcinoma. Flores A, Grant W, White AC, Scumpia P, Takahashi R, Lowry WE. Exp Dermatol. 2016 Apr 20. doi: 10.1111/exd.13037.

Hmga2 is dispensable for cutaneous squamous cell carcinoma. White A, Flores A, Ong J, Lowry WE. Exp Dermatol. 2016 May;25(5):409-12. doi: 10.1111/exd.12978.

The NADPH-Production Enzyme Isocitrate Dehydrogenase Maintains Quiescence in Hair Follicle Stem Cells. Ambrus, AM., Lemons, J., Raitman, I., Krishnan, N., Jelinek, D., Suh, E., Remillard M., Shilo, L., Xiao, R., Flores, A., Wang, D., White, A., Lowry, W., Coller, H. FASEB J. April 2016 20:1260.5.