Student Publication Archive

A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation. Tong AJ, Liu X, Thomas BJ, Lissner MM, Baker MR, Senagolage MD, Allred AL, Barish GD, Smale ST. Cell. 2016 Mar 24;165(1):165-79. doi: 10.1016/j.cell.2016.01.020. Epub 2016 Feb 25.

Cover image Cell Host & MicrobeFerrari R, Gou D, Jawdekar G, Johnson SA, Nava M, Su T, Yousef AF, Zemke NR, Pellegrini M, Kurdistani SK, Berk AJ.Adenovirus small E1A employs the lysine acetylases p300/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection. Cell Host Microbe. 2014 Nov 12;16(5):663-76. doi: 10.1016/j.chom.2014.10.004. Epub 2014 Nov 12. PubMed PMID: 25525796; PubMed Central PMCID: PMC4418520.

Association of Systemic Sclerosis With a Unique Colonic Microbial Consortium. Volkmann ER, Chang YL, Barroso N, Furst DE, Clements PJ, Gorn AH, Roth BE, Conklin JL, Getzug T, Borneman J, McGovern DP, Tong M, Jacobs JP, Braun J. Arthritis Rheumatol. 2016 Jun;68(6):1483-92. doi: 10.1002/art.39572.

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity. Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S, Griner S, Jiang L, Glabe CG, Westermark GT, Gonen T, Eisenberg DS. Elife. 2017 Jan 3;6. pii: e19273. doi: 10.7554/eLife.19273.

Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal. Kattke MD, Chan AH, Duong A, Sexton DL, Sawaya MR, Cascio D, Elliot MA, Clubb RT. PLoS One. 2016 Dec 9;11(12):e0167763. doi: 10.1371/journal.pone.0167763.

Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. Soriaga AB, Sangwan S, Macdonald R, Sawaya MR, Eisenberg D. J Phys Chem B. 2016 Jul 7;120(26):5810-6. doi: 10.1021/acs.jpcb.5b09981. Epub 2016 Jan 11.

STEM CELLSBaldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman ML, Cooper AR, Masiuk K, Hollis RP, Kohn DB.Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells. 2015 May;33(5):1532-42. doi: 10.1002/stem.1957. PubMed PMID: 25588820.

Exon Skipping Therapy. Young CS, Pyle AD. Cell. 2016 Nov 17;167(5):1144. doi: 10.1016/j.cell.2016.10.050.

Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma. Lowry WE, Flores A, White AC. J Invest Dermatol. 2016 May 7. pii: S0022-202X(16)30978-2. doi: 10.1016/j.jid.2016.03.017. [Epub ahead of print] Review.

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. Nature. 2016 May 11;534(7605):124-8. doi: 10.1038/nature17674.

Induction of HOXA genes in hESC-derived HSPC by two-step differentiation and RA signaling pulse.Dou DR, Calvanese V, Saarikoski P, Galic Z, Mikkola HKA.  Nature Protocol Exchange doi:10.1038/protex.2016.035.

Interferon Stimulated Gene Expression in HIV/HCV Coinfected Patients Treated with Nitazoxanide/Peginterferon-Alfa-2a and Ribavirin. Petersen T, Lee YJ, Osinusi A, Amorosa VK, Wang C, Kang M, Matining R, Zhang X, Dou D, Umbleja T, Kottilil S, Peters MG. AIDS Res Hum Retroviruses. 2016 Jul;32(7):660-7. doi: 10.1089/aid.2015.0236. Epub 2016 Mar 14.

Narsis Attar & Siavash Kurdistani. Layered regulation of the epigenome and its link to cellular metabolism and physiology. Am. Assoc. Cancer Res. Educ. Book, April 2014

Leukocyte Lysis and Cytokine Induction by the Human Sexually Transmitted Parasite Trichomonas vaginalis. Mercer F, Diala FG, Chen YP, Molgora BM, Ng SH, Johnson PJ. PLoS Negl Trop Dis. 2016 Aug 16;10(8):e0004913. doi: 10.1371/journal.pntd.0004913. eCollection 2016 Aug.

Mechanisms of host seeking by parasitic nematodes. Gang SS, Hallem EA. Mol Biochem Parasitol. 2016 May 17. pii: S0166-6851(16)30058-5. doi: 10.1016/j.molbiopara.2016.05.007.

Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Dou DR, Calvanese V, Sierra MI, Nguyen AT, Minasian A, Saarikoski P, Sasidharan R, Ramirez CM, Zack JA, Crooks GM, Galic Z, Mikkola HK. Nat Cell Biol. 2016 Jun;18(6):595-606. doi: 10.1038/ncb3354.

Posttranscriptional Regulation of Gcr1 Expression and Activity Is Crucial for Metabolic Adjustment in Response to Glucose Availability. Hossain MA, Claggett JM, Edwards SR, Shi A, Pennebaker SL, Cheng MY, Hasty J, Johnson TL. Mol Cell. 2016 May 5;62(3):346-58. doi: 10.1016/j.molcel.2016.04.012.

Potential for treatment and a Zika virus vaccine. Quanquin N, Wang L, Cheng G. Curr Opin Pediatr. 2016 Nov 30. [Epub ahead of print]

Preventing malaria in HIV-infected pregnant women. Bulterys PL, Kaplan JE, Gutman J. Clin Infect Dis. 2014 Mar;58(5):660-2. doi: 10.1093/cid/cit805. Epub 2013 Dec 12.

Screening for novel small molecule inhibitors targeting the assembling of influenza virus polymerase complex by a BiLC-based reporter system. Li C, Wang Z, Cao Y, Wang L, Ji J, Chen Z, Deng T, Jiang T, Cheng G, Qin FX. J Virol. 2016 Dec 28. pii: JVI.02282-16. doi: 10.1128/JVI.02282-16. [Epub ahead of print]

Chowdhury C, Chun S, Pang A, Sawaya MR, Sinha S, Yeates TO, Bobik TA. Selective molecular transport through the protein shell of a bacterial microcompartment organelle. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):2990-5. doi: 10.1073/pnas.1423672112. Epub 2015 Feb 23. PubMed PMID: 25713376; PubMed Central PMCID: PMC4364225.

The function of the PduJ microcompartment shell protein is determined by the genomic position of its encoding gene. Chowdhury C, Chun S, Sawaya MR, Yeates TO, Bobik TA. Mol Microbiol. 2016 Sep;101(5):770-83. doi: 10.1111/mmi.13423.

The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading. Kim EW, Nadipuram SM, Tetlow AL, Barshop WD, Liu PT, Wohlschlegel JA, Bradley PJ. mSphere. 2016 Mar 23;1(2). pii: e00045-16. doi: 10.1128/mSphere.00045-16. eCollection 2016 Mar-Apr.