Date time Location Name Title Address Host Notes Scopre Thesis 2000-10-05 4 PM 159 Boyer Hall Juan Bonifacino Adaptor Family and Friends: Component of the Lysosome Biogenesis Machinery NIH, Bethesda, MD Juan Bonifacino Host: Ayyappan Rajasekaran No 2000-11-30 4 PM 159 Boyer Hall Beverly Emerson Selective Gene Regulation by Chromatin Remodeling Complexes Regulatory Biology Laboratory, Salk Institute, La Jolla, CA Beverly Emerson Mike Carey, ext. 67859 Host: Mike Carey, ext. 67859 No 2000-12-07 4 PM 159 Boyer Hall Xiadong Wang The Role of Mitochondria in Apoptosis University of Texas Southwestern Medical Center, Dallas, TX Xiadong Wang Host: Fuyu Tamanoi, ext. 67318 Host: Fuyu Tamanoi, ext. 67318 No 2001-01-01 No 2001-01-01 4 PM 159 Boyer Hall MBI/ACCESS No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-01 4 PM 159 Boyer Hall No 2001-01-10 4 PM 159 Boyer Hall Dr. Philip Beachy TBD Molecular Biology and GeneticsJohns Hopkins School of Medicine Dr. Philip Beachy Fuyu Tamanoi No 2001-01-11 4 PM 159 Boyer Hall Dr. Elizabeth Finch Postsynaptic Calcium Signaling by IP3 in Cerebellar Long-Term Depression Department of Cell Biology, Emory University School of Medicine, Decatur, GA Dr. Elizabeth Finch No 2001-01-18 4 PM 159 Boyer Hall Dr. Joanne Chory Steroid Hormones in Plant Development Department of Plant Biology, Salk Institute for Biological Studies, La Jolla Dr. Joanne Chory No 2001-01-25 4 PM 159 Boyer Hall Dr. Hidde Ploegh The Cell Biology of Antigen Presentation: What Viruses Know and What We Must Learn Department of Pathology, Harvard Medical School, Boston, MA Dr. Hidde Ploegh No 2001-02-01 4 PM 159 Boyer Hall Dr. Sandra Schmid Dynamin: What's a GTPase Like You doing in a Place Like This? Department of Cell Biology, Scripps Research Institute, La Jolla Dr. Sandra Schmid David Meyer, x63122 Host: David Meyer, x63122 No 2001-02-08 4 PM 159 Boyer Hall Eugene Johnson Critical Events in Neuronal Programmed Cell Death Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louise, MO Eugene Johnson Harley Kornblum ext.47866 Host: Harley Kornblum ext.47866 No 2001-02-15 4 PM 159 Boyer Hall Edward Mocarski Cytomegalovirus-Encoded Chemokines in Pathogenesis Department of Microbiology & Immunology, Stanford University School of Medicine Edward Mocarski Ren Sun ext. 66483 Host: Ren Sun ext. 66483 No 2001-02-22 4 PM 159 Boyer Hall Norbert Perrimon Signal Transduction in Drosophila Department of Microbiology & Immunology, Harvard Medical School, Boston, MA Norbert Perrimon Judith Lengyel ext. 53298 Host: Judith Lengyel ext. 53298 No 2001-03-01 4 PM 159 Boyer Hall Dimitri Thomas Activation and Repression of Transcription by the IFN-beta Enhanceosome Department of Biochemistry & Molecular Biophysics, Columbia University, New York, NY Dimitri Thomas Mike Carey ext. 67859 Host: Mike Carey ext. 67859 No 2001-03-08 4 PM 159 Boyer Hall David Livingston - THIS SEMINAR HAS BEEN CANCELLED Dana Farber Cancer Institute, Harvard University, Boston, MA David Livingston - THIS SEMINAR HAS BEEN CANCELLED Ren Sun ext. 45557 Host:Ren Sun ext. 45557 No 2001-03-15 4 PM 159 Boyer Hall Geraldine Seydoux Generation of Assymmetry in the C. elegans Embryo Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, MD Geraldine Seydoux Gerry Weinmaster ext. 66446 Host: Gerry Weinmaster ext. 66446 No 2001-04-04 4:00 PM 159 Boyer Hall Ronald A. Milligan, PhD "The Mechanisms of Action of Molecular Motors" Department of Cell Biology, The Scripps Research Institute, La Jolla CA Ronald A. Milligan, PhD Host: Guido Zampighi, x56430 No 2001-04-05 4 PM 159 Boyer Hall Detlef Weigel Linking Floral Induction and Floral Patterning Department of Plant Molecular & Cellular Biology, Salk Institute for Biological Studies, La Jolla, CA Detlef Weigel Sioux Christensen, ext. 40018 No 2001-04-11 4 PM 159 Boyer Hall Douglas C. Rees, PhD Crystallographic Studies of Membrane Proteins Division of Chemistry & Chemical Engineering, HHMI, California Institute of Technology, Pasadena Douglas C. Rees, PhD Host: David Eisenberg, x53754 No 2001-05-02 4 PM 159 Boyer Hall Cori Bargmann, PhD Genetic Dissection of Signaling Pathways in Neural Development Department of Anatomy, UC San Francisco Cori Bargmann, PhD Host: Larry Zipursky, x52834 No 2001-05-03 4 PM 159 Boyer Hall Dr. Stephen Goff Regulators and Effectors of the Abelson Kinase Department of Biochemistry & Molecular Biophysics, Columbia University, NY Dr. Stephen Goff John Colicelli, x67800 No 2001-05-10 4 PM 159 Boyer Hall Dr. Linda Buck Deconstructing Smell Department of Neurobiology, Harvard Dr. Linda Buck Gerry Weinmaster, x69446 No 2001-05-17 4 PM 159 Boyer Hall Dr. Joel Richter Translational Control at the Synapse: Lessons from Xenopus Oocytes Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester Dr. Joel Richter Arnie Berk, x66298 No 2001-05-24 4 PM 159 Boyer Hall Dr. Jorge Galan Host Mimicry and Infliction of Limited Damage: Alternative Strategies for the Modulation of Cellular Functions by Bacterial Pathogens Department of Microbial Pathogenesis, Yale Dr. Jorge Galan Jeff F. Miller, x67926 No 2001-05-31 4 PM 159 Boyer Hall Dr. Peter Wright TBA Department of Molecular Biology, Scripps Research Institute Dr. Peter Wright Robert Clubb, x62334 No 2001-06-07 4 PM 159 Boyer Hall Dr. Christopher Glass Regulation of Macrophage Gene Expression by Nuclear Hormone Receptors Department of Cellular and Molecular Medicine, UCSD Dr. Christopher Glass Peter Edwards, x63717 No 2001-10-04 4 PM 159 Boyer Hall Dr. William Kaelin Molecular Pathogenesis of the von Hippel-Lindau Hereditary Cancer Syndrome: Implications for Oxygen Sensing Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA Dr. William Kaelin Arnie Berk, x66298 No 2001-10-11 4 PM 159 Boyer Hall Dr. Elaine Fuchs Directing Stem Cell Lineages in the Skin Department of Molecular Genetics & Cell Biology, University of Chicago, IL Dr. Elaine Fuchs A. Rajasekaran, x51199 No 2001-10-18 4 PM 159 Boyer Hall Dr. Linda Hicke Roles of Ubiquitin in Signaling Receptor Endocytosis Department of Biochemistry, Molecular & Cell Biology, Northwestern University, Evanston, IL Dr. Linda Hicke Greg Payne, x63121 No 2001-10-25 4 PM 159 Boyer Hall Dr. Mary Moore Mechanisms of Nuclear Transport Department of Molecular & Cell Biology, Baylor College of Medicine, Houston, TX Dr. Mary Moore Carla Koehler, x44834 No 2001-11-01 4 PM 159 Boyer Hall Dr. Danny Schnell The Protein Import Machinery of Chloroplasts Department of Biochemistry & Molecular Biology, University of Massachusetts, Amherst Dr. Danny Schnell Sabeeha Merchant, x58300 No 2001-11-08 4 PM 159 Boyer Hall Dr. Jonathan Weissman Mechanism of Amyloid Formation and Propagation: Lessons from a Yeast Prion Department of Cellular & Medical Pharmacology, UCSF Dr. Jonathan Weissman Todd Yeates, x64866 No 2001-11-15 4 PM 159 Boyer Hall TBA No 2001-11-29 4 PM 159 Boyer Hall Dr. Daphne Preuss How Plants Choose Their Mates Department of Molecular Genetics & Cell Biology, University of Chicago, IL Dr. Daphne Preuss Sabeeha Merchant, x58300 No 2001-12-06 4 PM 159 Boyer Hall Dr. David Livingston Functional Analysis of the BRCA1 and 2 Gene Products Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA Dr. David Livingston Ren Sun, x45557 No 2002-01-10 4 PM 159 Boyer Hall Dr. Philip Beachy Hedgehog signaling in development and disease Department of Molecular Biology & Genetics, Johns Hopkins School of Medicine, Baltimore MD Dr. Philip Beachy Fuyu Tamanoi x67318 No 2002-01-17 4 PM 159 Boyer Hall Dr. Erin O'Shea Signaling Phosphate Starvation Department of Biochemistry & Biophysics, UC San Francisco Dr. Erin O'Shea Guillaume Chanfreau, 310 794-4399 http://www.ucsf.edu/ekolab/ No 2002-01-24 4 PM 159 Boyer Hall Dr. Pamela Larsen DAF-2 Insulin-like Receptor Pathway Control of Expression and Physiology in Long-lived C. elegans Department of Chemistry and Biochemistry, UCLA Dr. Pamela Larsen Greg Payne, 310 206-3121 No 2002-01-31 4 PM 159 Boyer Hall Dr. Anjana Rao Gene Regulation by NFAT Transcription Factors in the Immune Response Department of Pathology, Harvard University School of Medicine, Boston MA Dr. Anjana Rao Steve Smale, 310 206-4777 No 2002-02-07 4 PM 159 Boyer Hall Dr. Jose Reichman Genome-wide Analyses of Arabidopsis Transcription Factors: From Sequence to Function Mendel Biotechnology Inc., Hayward CA Dr. Jose Reichman Chentao Lin, 310 206-9576 No 2002-02-14 4 PM 159 Boyer Hall Dr. Mina Bissell The Role of Extracellular Matrix and the Microenvironment in Regulation of Signaling in Normal and Malignant Breast: the Dominance of Tissue Structure Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley CA Dr. Mina Bissell Srinivasa Reddy, 310 206-3915 http://www.lbl.gov/lifesciences/BissellLab/main.html No 2002-02-21 4 PM 159 Boyer Hall Dr. Iain Mattaj The Ran GTPase as a Marker of Chromosome Position European Molecular Biology Laboratory, Heidelberg, Germany Dr. Iain Mattaj Doug Black, 310 794-7644 www-db.embl-heidelberg.de:4321/emblGroups/per_322.html No 2002-02-28 4 PM 159 Boyer Hall Dr. Mary Lou Guerinot Gene Discovery in Aid of Plant Nutrition, Human Health and Environmental Remediation Department of Biology, Dartmouth College, Hanover NH Dr. Mary Lou Guerinot Sabeeha Merchant, 310 825-8300 http://www.dartmouth.edu/~mcb/faculty/guerinot.html No 2002-03-07 4 PM 159 Boyer Hall Dr. Michael J. O'Donovan Mechanisms of Rhythmogenesis in the Spinal Cord National Institute of Neurological Disorders and Stroke, NIH, Bethesda MD Dr. Michael J. O'Donovan Jack Feldman, 310 825-2123 http://www.ninds.nih.gov/about_ninds/labs/35.htm No 2002-03-14 4 PM 159 Boyer Hall Dr. Susan Wente Connections Between Nucleoporins, mRNA Export and Inositol Signaling Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis MO Dr. Susan Wente Greg Payne, 310 206-3121 http://www.wentelab.wustl.edu/ No 2002-04-04 4:00 PM 159 Boyer Hall Ronald A. Milligan, PhD Structure and Design of Molecular Motors Department of Cell Biology, The Scripps Research Institute, La Jolla CA Ronald A. Milligan, PhD Guido Zampighi, x56430 No 2002-04-11 4 PM 159 Boyer Hall Douglas C. Rees, PhD Crystallographic Studies of Membrane Proteins Division of Chemistry & Chemical Engineering, HHMI, California Institute of Technology, Pasadena Douglas C. Rees, PhD David Eisenberg, x53754 No 2002-04-18 4 PM 159 Boyer Hall Thomas M. Jessell, PhD The Specification of Motor Neuron Identity and Connectivity Department of Biochemistry & Molecular Biophysics, Center for Neurobiology and BehaviorColumbia University, New York NY Thomas M. Jessell, PhD Larry Zipursky, x52834 No 2002-04-25 4 PM 159 Boyer Hall Bernard Moss, MD PhD Intracellular Assembly and Movement of Vaccinia Virus Laboratory of Viral Diseases, National Institute of Allergy & Infectious DiseasesNational Institutes of Health, Bethesda MD Bernard Moss, MD PhD Info: Gail Panatier, x51018 No 2002-05-02 4 PM 159/173 Boyer Cori Bargmann, PhD Genetic Dissection of Signaling Pathways in Neural Development Department of Anatomy, UC San Francisco Cori Bargmann, PhD Larry Zipursky, x52834 No 2002-05-09 4 PM 159/173 Boyer Joan Ruderman, PhD Regulation of the Mitotic Kinase Aurora A, a Potent Proto-Oncogene Department of Cell Biology, Harvard Medical School, Boston MA Joan Ruderman, PhD Judith Lengyel, x53298 No 2002-05-16 4 PM 159/173 Boyer Channing J. Der, PhD Ras and Rho GTPases, Signaling and Transformation Department of PharmacologyLineberger Comprehensive Cancer CenterUniversity of North Carolina-Chapel Hill School of Medicine Channing J. Der, PhD John Colicelli, x67800 No 2002-05-23 4 PM 159/173 Boyer Konstantin V. Severinov, PhD Structure-based Analysis of RNA Polymerase Function Waksman Institute of MicrobiologyDepartment of Genetics, Rutgers University, Piscataway NJ Konstantin V. Severinov, PhD Al Courey, x52530 No 2002-05-30 4 PM 159/173 Boyer Stephen G. Young, MD Physiologic Relevance of Zmpste24 and Icmt, Two Posttranslational Protein Processing Enzymes Gladstone Institute of Cardiovascular DiseaseDivision of Cardiology, School of Medicine, UC San Francisco Stephen G. Young, MD Cathy Clarke, x50771 No 2002-06-06 4 PM 159/173 Boyer Robert M. Stroud, PhD The Structure and Selectivity of an Ancient Transmembrane Channel Family: the Aquaporins Macromolecular Structure GroupDepartment of Biochemistry & Biophysics, UC San Francisco Robert M. Stroud, PhD David Eisenberg, x53754 No 2002-10-03 4 PM 159 Boyer Hall Raju Kucherlapati, PhD Multiple Roles of DNA Repair Genes Harvard Partners Center for Genetics & GenomicsDepartment of Genetics, Harvard Medical School, Boston MA Raju Kucherlapati, PhD Karen Lyons, x55480 No 2002-10-10 4 PM 159 Boyer Hall Timothy Hla, PhD Cox-2 Pathway in Tumorigenesis Center for Vascular Biology, Department of PhysiologyUniversity of Connecticut Health Center, Farmington Timothy Hla, PhD Luisa Iruela-Arispe, x45763 No 2002-10-17 4 PM 159 Boyer Hall Eduardo Perozo, PhD The Mechanics of Mechanosensitive Channel Gating Interdisciplinary Program in BiophysicsDepartment of Molecular Physiology and Biological PhysicsUniversity of Virginia, Charlottesville Eduardo Perozo, PhD James Bowie, x64747 No 2002-10-24 4 PM 159 Boyer Hall Paul W. Sternberg, PhD Signaling During C. elegans Behavior and Development Division of Biology, Howard Hughes Medical InstituteCalifornia Institute of Technology, Pasadena Paul W. Sternberg, PhD Alexander van der Bliek, x59779 No 2002-10-31 4 PM 159 Boyer Hall Martin A. Schwartz, PhD Regulation of Cell Migration, Growth and Survival by Integrins Department of Microbiology, University of Virginia, Charlottesville Martin A. Schwartz, PhD Luisa Iruela-Arispe, x45763 No 2002-11-07 4 PM 159 Boyer Hall Lynne E. Maquat, PhD Nonsense-mediated mRNA Decay in Mammals: Evidence for a 'Pioneer' Round of Translation as a Means of mRNA Quality Control Department of Biochemistry and BiophysicsSchool of Medicine and Dentistry, University of Rochester NY Lynne E. Maquat, PhD Sabeeha Merchant, x58300 No 2002-11-14 4 PM 159 Boyer Hall Peter B. Moore, PhD Structure and Function in the Large Ribosomal Subunit Department of Chemistry, Yale University, New Haven CT Peter B. Moore, PhD James Lake, x52546 No 2002-11-21 4 PM 159 Boyer Hall Jeannie T. Lee, MD PhD Regulation of X-chromosome Inactivation by Non-coding RNAs Howard Hughes Medical InstituteDepartment of Genetics, Harvard Medical SchoolDepartment of Molecular BiologyMassachusetts General Hospital, Boston Jeannie T. Lee, MD PhD York Marahrens, x72466 No 2002-12-05 4 PM 159 Boyer Hall Kevin P. Campbell, PhD New Insights into the Pathogenesis of Muscular Dystrophy Department of Physiology and BiophysicsUniversity of Iowa College of Medicine Kevin P. Campbell, PhD James Tidball, x63395 No 2003-01-01 4 PM 159 Boyer Hall No 2003-01-01 4 PM 159 Boyer Hall No 2003-01-08 4 PM 159 Boyer Hall Jerry Hart To be announced Johns Hopkins Medical Institute Jerry Hart Liz Neufeld, x57149 No 2003-01-09 4 PM 159 Boyer Hall Douglas C. Wallace, PhD Mitochondrial Defects and Human Evolution and Disease Center for Molecular and Mitochondrial Medicine and Genetics (MAMMAG)Departments of Ecology & Evolutionary Biology and Biological Chemistry, UC Irvine Douglas C. Wallace, PhD Carla Koehler, x44834 No 2003-01-16 4 PM 159 Boyer Hall Gregory Hannon, PhD RNAi: Mechanism and Application Cold Spring Harbor Laboratory, NY Gregory Hannon, PhD Fuyuhiko Tamanoi, x67318 No 2003-01-23 4 PM 159 Boyer Hall Wendell Lim, PhD Switches and Scaffolds: Taking Apart Modular Signaling Proteins Department of Cellular and Molecular Pharmacology, UC San Francisco Wendell Lim, PhD James Bowie, x64747 No 2003-01-30 4 PM 159 Boyer Hall David Bentley, PhD Integration of Transcription with Pre-mRNA Processing Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center David Bentley, PhD Guillaume Chanfreau, x54399 No 2003-02-06 4 PM 159 Boyer Hall Douglas Koshland, PhD Chromosome Folding and Genome Integrity Carnegie Institution of Washington, Baltimore MD Douglas Koshland, PhD Hong Wu, x55160 No 2003-02-13 4 PM 159 Boyer Hall Dafna Bar-Sagi, PhD Feedback Control of Ras Signaling Department of Molecular Genetics & MicrobiologySUNY at Stony Brook Dafna Bar-Sagi, PhD Fuyu Tamanoi, x67318 No 2003-02-20 4 PM 159 Boyer Hall Mary Beth Mudgett, PhD Microbial Pathogenesis and Plant Innate Immunity: Who is in Control Department of Biological Sciences, Stanford University Mary Beth Mudgett, PhD Steve Clarke, x58754 No 2003-02-27 4 PM 159/173 Boyer Joan Sawyer Steffan, PhD Transcriptional Dysregulation in Huntington's Disease and Suppression of Polyglutamine Pathogenesis in Drosophila by Histone Deacetylase Inhibitor Therapy Department of Psychiatry & Human BehaviorCollege of Medicine, UC Irvine Joan Sawyer Steffan, PhD Paul Micevych, x68265 No 2003-03-06 4 PM 159/173 Boyer Peter Quail, PhD Phytochrome Photosensory Signaling Networks Department of Plant and Microbial Biology, UC Berkeley Peter Quail, PhD Elaine Tobin, x57700 No 2003-03-13 4 PM 159/173 Boyer Gregg L. Semenza, MD PhD Molecular Mechanisms of Oxygen Homeostasis Department of Pediatrics, McKusick-Nathans Institute of Genetic MedicineJohns Hopkins University School of Medicine, Baltimore MD Gregg L. Semenza, MD PhD Oliver Hankinson, x52936 No 2003-04-03 4 PM 159/173 Boyer Phillip D. Zamore, PhD Ancient Pathways Programmed by Small RNAs Department of Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School Phillip D. Zamore, PhD Guillaume Chanfreau, x54399 No 2003-04-10 4 PM 159/173 Boyer Susan Baserga, MD PhD New Insights into Eukaryotic Ribosome Biogenesis Department of Therapeutic Radiology, Yale University School of Medicine Susan Baserga, MD PhD Guillaume Chanfreau, x54399 No 2003-04-17 4 PM 159/173 Boyer Thomas P. Stossel, MD Regulation of Actin Remodeling and Some of Its Clinical Implications Cell Biology and Cytoskeleton GroupDivision of Hematology, Brigham and Women's HospitalDepartment of Medicine, Harvard Medical School Thomas P. Stossel, MD Ayyappan Rajasekaran, x51199 No 2003-04-24 4 PM 159/173 Boyer Ned Ruby, PhD Initiating a Beneficial Infection: Bacterial Signaling in the Vibrio-squid Symbiosis Pacific Biochemical Research Center, University of Hawaii Ned Ruby, PhD Robert Gunsalus, x68201 No 2003-05-01 4 PM 159 Boyer Hall Joseph R. Ecker, PhD Weeding Out the Genes: Genome-wide Functional Analysis in Arabidopsis Plant Biology Laboratory, The Salk Institute for Biological Studies Joseph R. Ecker, PhD Chentao Lin, x69576 No 2003-05-08 4 PM 159 Boyer Hall David C. Page, MD Rethinking the Rotting Y Chromosome Department of Biology, MIT David C. Page, MD Art Arnold, x52169 No 2003-05-15 4 PM 159 Boyer Hall Stephen T. Warren, PhD Fragile X Syndrome: Mechanisms of Disease Department of Human Genetics, Emory University School of Medicine Stephen T. Warren, PhD Rachelle Crosbie, x42103 No 2003-05-22 4 PM 159 Boyer Hall Vivek Malhotra, PhD Regulation of Protein Transport from the TGN and Golgi Fragmentation during Mitosis Division of Biological Sciences, Cell & Developmental Biology, UC San Diego Vivek Malhotra, PhD Greg Payne, x63121 No 2003-05-29 4 PM 159 Boyer Hall Denise Montell, PhD Regulation of Cell Motility and the Cytoskeleton in Drosophila Border Cells and Human Ovarian Cancer Cells Department of Biological Chemistry, John Hopkins Medical Institute Denise Montell, PhD Judith Lengyel, x53298 No 2003-10-02 4 PM 159 Boyer Hall Sue Bodine, PhD Unraveling the Mechanisms Responsible for Muscle Atrophy Exercise Biology Program and Dept. Human Physiology, Division of Biological Science and School of Medicine, UC Davis Sue Bodine, PhD Rachelle Crosbie, x42103 No 2003-10-09 4 PM 159 Boyer Hall Jian Zuo, PhD Genetic Analysis of Mammalian Hearing Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis TN Jian Zuo, PhD Ming Guo, x67597 No 2003-10-16 4 PM 159 Boyer Hall Kathleen Collins, PhD Assembly and Activity of Telomerase Ribonucleoproteins Molecular and Cell Biology, UC Berkeley Kathleen Collins, PhD Juli Feigon, x66922 No 2003-10-23 4 PM 159 Boyer Hall Cecile Pickart, PhD Signaling by Ubiquitin in DNA Repair Biochemistry and Molecular Biology, Johns Hopkins University, Baltimore MD Cecile Pickart, PhD Greg Payne, x63121 No 2003-10-30 4 PM 159 Boyer Hall W. James Nelson, PhD Biogenesis of Epithelial Cell Polarity Molecular & Cellular Physiology, Stanford University School of Medicine W. James Nelson, PhD A. Rajasekaran, x51199 No 2003-11-06 4 PM 159 Boyer Hall Clifford Tabin, PhD New Insights into Hedgehog Signaling during Limb Patterning Genetics, Harvard Medical School, Boston MA Clifford Tabin, PhD Xianjie Yang, x57020 No 2003-11-13 4 PM 159 Boyer Hall Steven M. Block, PhD Using Optical Tweezers to Study Biological Motors Biological Sciences and Applied Physics, Stanford University Steven M. Block, PhD Emil Reisler, x52668 No 2003-11-20 4 PM 159 Boyer Hall Craig L. Peterson, PhD Chromatin Remodeling for Transcription and DNA Repair University of Massachusetts Medical School, Worcester Craig L. Peterson, PhD Jim Bowie, x64747 No 2003-12-04 4 PM 159 Boyer Hall Bruce Edgar, PhD Control of Growth and Organ Size in Drosophila Fred Hutchinson Cancer Research Center, Seattle WA Bruce Edgar, PhD Fuyu Tamanoi, x67318 No 2003-12-11 4 PM NPI Aud Sydney Brenner, DPhil Inverse Genetics Salk Institute for Biological Studies, La Jolla CA Sydney Brenner, DPhil Jim Lake, x52546 No 2004-01-08 4 PM 159 Boyer Hall Gerald Hart, PhD Dynamic Interplay between O-GlcNAc and O-phosphate: Roles in Transcription, Signaling and in Cellular Response to Stress Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore MD Gerald Hart, PhD Liz Neufeld, x57149 No 2004-01-15 4 PM 159 Boyer Hall Adrian Krainer, PhD Determinants of Exon Identity Cold Spring Harbor Laboratory, NY Adrian Krainer, PhD Doug Black, x47644 No 2004-01-22 4 PM 159 Boyer Hall Erkki Ruoslahti, MD PhD Vascular Zipcodes in Tumor Angiogenesis and Metastasis The Burnham Institute, La Jolla CA Erkki Ruoslahti, MD PhD Lily Wu, x44390 No 2004-01-29 4 PM 159 Boyer Hall Arthur E. Johnson, PhD Cholesterol-Dependent Structural Transitions Initiate Oligomerization and β-Barrel Pore Formation by a Bacterial Protein Toxin College of Medicine, Texas A&M University System Health Science Center, College Station Arthur E. Johnson, PhD Carla Koehler, x44834 No 2004-02-05 4 PM 159 Boyer Hall Julie Theriot, PhD Life on the Inside: Cell Biology of Bacterial Infections in Intestinal and Bladder Epithelia Biochemistry, Stanford University Medical School, Palo Alto CA Julie Theriot, PhD Rachelle Crosbie, x42103Kent Hill, x70546 No 2004-02-12 4 PM 159 Boyer Hall George A. O'Toole, PhD P. aeruginosa Biofilm Development: Architecture and Antibiotics Microbiology and Immunology, Dartmouth Medical School, Hanover NH George A. O'Toole, PhD Beth Lazazzera, x44804 No 2004-02-19 4 PM 159 Boyer Hall Shiv Grewal, PhD RNAi-mediated Epigenetic Control of the Genome Laboratory of Molecular Cell Biology, Center for Cancer Research, National Cancer Institute, Bethesda MD Shiv Grewal, PhD Al Courey, x52530 No 2004-02-26 4 PM 159 Boyer Hall James L. Manley, PhD mRNA Processing and the Integration of Nuclear Events Biological Sciences, Columbia University, New York NY James L. Manley, PhD Harold Martinson, x53767 No 2004-03-04 4 PM 159 Boyer Hall Catherine L. Drennan, PhD Surprising Cofactors in Metalloenzymes Chemistry, Massachusetts Institute of Technology, Cambridge Catherine L. Drennan, PhD Sabeeha Merchant, x58300 No 2004-03-11 4 PM 159 Boyer Hall Nikolaus Pfanner, MD Mitochondrial Machineries for Transport and Assembly of Precursor Proteins Institute for Biochemistry and Molecular Biology, University of Freiburg, Germany Nikolaus Pfanner, MD Carla Koehler, x44834 No 2004-04-08 4 PM 159 Boyer Hall A. Keith Dunker, PhD Intrinsic Disorder and Protein Function Center for Computational Biology & Bioinformatics, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis A. Keith Dunker, PhD Steve Clarke, x58754 No 2004-04-15 4 PM 159 Boyer Hall Richard Vierstra, PhD The Ubiquitin/26S Proteasome Pathway: the 800-lb Gorilla in Post-transcriptional Regulation Genetics, University of Wisconsin, Madison Richard Vierstra, PhD Chentao Lin, x69576 No 2004-04-22 4 PM 159 Boyer Hall Louise Prakash, PhD Translesion Synthesis DNA Polymerases of Yeast and Human Sealy Center for Molecular Science, University of Texas Medical Branch, Galveston Louise Prakash, PhD Guillaume Chanfreau, x54399 No 2004-04-29 4 PM 159 Boyer Hall Jay C. Dunlap, PhD Genetic and Molecular Dissection of a Simple Circadian System Genetics, Dartmouth Medical School, Hanover NH Jay C. Dunlap, PhD Elaine Tobin, x57700 No 2004-05-06 4 PM 159 Boyer Hall Susan S. Taylor, PhD Dynamics of Signaling by cAMP-dependent Protein Kinase Chemistry and Biochemistry, UC San Diego Susan S. Taylor, PhD Sabeeha Merchant, x58300 No 2004-05-13 4 PM 159 Boyer Hall Roy R. Parker, PhD Life, Death and Midlife Crisis of mRNA in Simple Eukaryotic Cells Molecular & Cellular Biology, Biochemistry & Molecular Biophysics, University of Arizona, Tucson Roy R. Parker, PhD Guillaume Chanfreau, x54399 No 2004-05-20 4 PM 159 Boyer Hall Deborah Morrison, PhD Function and Regulation of RAS Signaling: The KSR Scaffold Center for Cancer Research, NCI/NIH, Frederick MD Deborah Morrison, PhD John Colicelli, 310 625-5272 No 2004-05-27 4 PM 159 Boyer Hall Holly A. Ingraham, PhD Orphan Nuclear Receptors: Gene Dosage Effects and Ligand-independent Modulation Physiology, UC San Francisco Holly A. Ingraham, PhD Art Arnold, x52169 No 2004-06-03 4 PM 159 Boyer Hall Christian Tschudi, PhD The Mechanism and Biological Function of RNA Interference in Trypanosoma brucei Division of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven CT Christian Tschudi, PhD Dan Ray, x54178 No 2004-06-10 4 PM 159 Boyer Hall Dianne K. Newman, PhD How Bacteria Respire Minerals Geobiology & Environmental Science, Division of Geological & Planetary Sciences, California Institute of Technology, Pasadena CA Dianne K. Newman, PhD Joan Valentine, x59835 No 2004-09-30 4 PM 159 Boyer Hall Caroline Philpott, MD Pumping Iron: The Response to Iron Deprivation in Saccharomyces cerevisiae Liver Diseases Section, Digestive Diseases Branch, National Institute of Diabetes & Digestive & Kidney Diseases, NIH, Bethesda MD Caroline Philpott, MD Joan Valentine, x59835 No 2004-10-07 4 PM 159 Boyer Hall Roberto Kolter, PhD Biofilms: The Matrix Revisited Department of Microbiology & Molecular Genetics, Harvard Medical School, Boston MA Roberto Kolter, PhD Wen Shi, x58356 No 2004-10-14 4 PM 159 Boyer Hall Michael Rudnicki, PhD Molecular Regulation of Stem Cell Function during Regenerative Myogenesis Molecular Medicine, Ottawa Health Research Institute, Departments of Medicine, Cellular & Molecular Medicine, Faculty of Medicine, University of Ottawa, Ontario Canada Michael Rudnicki, PhD Melissa Spencer, x45225 No 2004-10-21 4 PM 159 Boyer Hall Jeffrey Esko, PhD Glycans: Novel Targets for Tumor Therapy Department of Cellular and Molecular Medicine, UC San Diego, La Jolla CA Jeffrey Esko, PhD Linda Baum, x65985 No 2004-10-28 4 PM 159 Boyer Hall Michael A. Dyer, PhD The Role of the Rb Protein in Retinal Development and Retinoblastoma Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis TN Michael A. Dyer, PhD Evan Hsieh, x56992(Yang lab) No 2004-11-04 4 PM 159 Boyer Hall Richard Carthew, PhD Gene Silencing by RNA Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston IL Richard Carthew, PhD Ming Guo, x67597 No 2004-11-11 4 PM 159 Boyer Hall Veterans' Day Holiday Veterans' Day Holiday No 2004-11-18 4 PM 159 Boyer Hall Bruce Stillman, PhD The Origin Recognition Complex: Involvement in DNA Replication, Chromosome Segregation and Cytokinesis Cold Spring Harbor Laboratory, NY Bruce Stillman, PhD York Marahrens, x72466 No 2004-11-25 4 PM 159 Boyer Hall Thanksgiving Holiday Thanksgiving Holiday No 2004-12-02 4 PM 159 Boyer Hall Huntington F. Willard, PhD Genomic Approaches to Understanding the Function of Natural and Engineered Human Chromosomes Institute for Genome Sciences & Policy, Department of Molecular Genetics & Microbiology, Duke University, Durham NC Huntington F. Willard, PhD Tim Lane, x45799 No 2004-12-09 4 PM 159 Boyer Hall Kim Orth, PhD Black Death, Black Spot: The Diversity of YopJ-like Proteins Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas Kim Orth, PhD Ken Bradley, x67465 No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall Larry Goldstein To be announced University of California, San Diego, Howard Hughes Medical Institute Larry Goldstein Ming Guo , x67597 No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall Joel Rosenbaum, Ph.D. To be announced Dept. of Molecular, Cellular, and Developmental Biology, Yale University Joel Rosenbaum, Ph.D. Kent Hill x70546 No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-01 4 PM 159 Boyer Hall No 2005-01-06 4 PM 159 Boyer Hall David Baker, PhD Prediction and Design of Macromolecular Structures and Interactions Department of Biochemistry, University of Washington, Seattle David Baker, PhD Jim Bowie, x64747 No 2005-01-20 4 PM 159 Boyer Hall Richard M. Amasino, PhD The Epigenetic Memory of Winter: Vernalization and the Competence to Flower Department of Biochemistry, University of Wisconsin, Madison Richard M. Amasino, PhD Chentao Lin, x69576 No 2005-01-27 4 PM 159 Boyer Hall Daniel N. Hebert, PhD The Glycan Code, Carbohydrates Act as Maturation and Quality Control Tags in the Endoplasmic Reticulum Department of Biochemistry & Molecular Biology, University of Massachusetts, Amherst Daniel N. Hebert, PhD Carla Koehler, x44834 No 2005-02-03 4 PM 159 Boyer Hall Jeffrey S. Chamberlain, PhD Systemic Delivery of Micro-dystrophin Genes to Dystrophic Mice Department of Neurology, University of Washington School of Medicine, Seattle Jeffrey S. Chamberlain, PhD Melissa Spencer, x45225 No 2005-02-10 4 PM 159 Boyer Hall William M. Bement, PhD Conserved Signaling Mechanisms Control Single Cell Wound Healing and Cell Division Department of Zoology, University of Wisconsin, Madison William M. Bement, PhD Cameron Gundersen, x53423 No 2005-02-17 4 PM 159 Boyer Hall Kun-Liang Guan, PhD Regulation of Cell Growth and Cell Size by the TSC-mTOR Pathway Life Sciences Institute, Department of Biological Chemistry, University of Michigan, Ann Arbor Kun-Liang Guan, PhD Fuyu Tamanoi, x67318 No 2005-02-24 4 PM 159 Boyer Hall Eric S. Lander, PhD Beyond the Human GenomeRSVP/Info: 310.206.3535 ***Location: Franz Hall Room 1178*** Massachusetts Institute of Technology and Harvard Medical School, Boston Eric S. Lander, PhD UCLA CollegeMBIChem&Biochem No 2005-03-03 4 PM 159 Boyer Hall Jonathan D. Gitlin, MD Interplay of Nutrition and Genetics in Zebrafish Embryonic Development Department of Pediatrics, School of Medicine, Washington University, St. Louis MO Jonathan D. Gitlin, MD Sabeeha Merchant, x58300 No 2005-03-10 4 PM 159 Boyer Hall Laura Lillien, PhD Progenitor Diversity in the Central Nervous System Center for Neuroscience, University of Pittsburgh, PA Laura Lillien, PhD Xian-Jie Yang, x57020 No 2005-04-07 4 PM 159 Boyer Hall Liang Tong, PhD Structural Studies of Fatty Acid Metabolism and Relevance to the Obesity Epidemic Department of Biological Sciences, Columbia University, New York NY Liang Tong, PhD Ren Sun, x45557 No 2005-04-14 4 PM 159 Boyer Hall Carol Gross, PhD Regulating Transcription: The View from the Sigma Subunit of RNA Polymerase Departments of Stomatology and Microbiology & Immunology, UC San Francisco Carol Gross, PhD Reid Johnson, x57800 No 2005-04-21 4 PM 159 Boyer Hall Juli Feigon, PhD Structural and Functional Studies of Human Telomerase and Yeast RNase III Department of Chemistry & Biochemistry, UCLA Juli Feigon, PhD Arnie Berk, x66298 No 2005-04-28 4 PM 159 Boyer Hall A. J. Hudspeth, MD PhD Making an Effort to Listen: Mechanical Amplification by Novel Molecular Motors in the Ear Laboratory of Sensory Neuroscience, The Rockefeller University, New York NY A. J. Hudspeth, MD PhD Felix Schweizer, x45733 No 2005-05-05 4 PM 159 Boyer Hall Benoit de Crombrugghe, MD Cell Fate Determination and Cell Differentiation in Skeletal Tissues Department of Molecular Genetics, UT M.D. Anderson Cancer Center, Houston Benoit de Crombrugghe, MD Karen Lyons, x55480 No 2005-05-12 4 PM 159 Boyer Hall Peter McPherson, PhD Molecular Mechanisms in Clathrin-mediated Membrane Budding Revealed through Subcellular Proteomics McGill University, Quebec Canada Peter McPherson, PhD Greg Payne, x63121 No 2005-05-19 4 PM 159 Boyer Hall Pamela A. Silver, PhD Spatial Control, Perturbation and Redesign of Nuclear Programs Department of Systems Biology, Harvard Medical School and Department of Cancer Biology, Dana- Farber Cancer Institute, Boston MA Pamela A. Silver, PhD Minghua Nie, x64982(Courey lab) No 2005-05-26 4 PM 159 Boyer Hall Neal G. Copeland, PhD Harnessing Transposons for Cancer Gene Discovery Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick MD Neal G. Copeland, PhD Suraj Bhat, x59543 No 2005-06-02 4 PM 159 Boyer Hall June B. Nasrallah, PhD Recognition and Rejection of Self in Plant Reproduction Department of Plant Biology, Cornell University, Ithaca NY June B. Nasrallah, PhD Elaine Tobin, x57700 No 2005-06-09 4 PM 159 Boyer Hall Alexander S. Raikhel, PhD Gene Regulatory Cascades Connecting Blood Feeding, Egg Production and Pathogen Transmission in Mosquitoes Center for Disease-Vector Research, Institute for Integrative Genome Biology, Department of Entomology, UC Riverside Alexander S. Raikhel, PhD Sabeeha Merchant, x58300 No 2005-09-29 4 PM 159 Boyer Hall Lawrence S.B. Goldstein, Ph.D. Linking Stem Cells and Molecular Motors to Signaling and Neurodegenerative Disease Howard Hughes Medical Institute, Department of Cellular & Molecular MedicineUC San Diego School of Medicine, La Jolla CA Lawrence S.B. Goldstein, Ph.D. Ming Guo, x67597 No 2005-10-06 4 PM 159 Boyer Hall Jonathan P. Staley, Ph.D. Switches and Motors that Regulate the Activity and Specificity of the Spliceosome Department of Molecular Genetics & Cell Biology, University of Chicago, Illinois Jonathan P. Staley, Ph.D. Guillaume Chanfreau, x54399 No 2005-10-13 4 PM 159 Boyer Hall Errol C. Friedberg, M.D. Multiple Specialized DNA Polymerases in Eukaryotic Cells: Deciphering their Biological Functions Department of Pathology, UT Southwestern Medical CenterDallas TX Errol C. Friedberg, M.D. Robert Schiestl, x72087Co-sponsor MolToxIDP No 2005-10-20 4 PM 159 Boyer Hall Fyodor A. Kondrashov Finding Pathogenic Mutations in Healthy Organisms: Results and Perspectives Section on Ecology, Behavior & Evolution, Division of Biological Sciences, UC San Diego Fyodor A. Kondrashov Yi Xing (Lee lab), x44026 No 2005-10-27 4 PM 159 Boyer Hall Laurie S. Kaguni, Ph.D. Biochemical Genetics of the Mitochondrial Replisome Department of Biochemistry and Molecular BiologyMichigan State University, East Lansing MI Laurie S. Kaguni, Ph.D. Dan Ray, x54178 No 2005-11-03 4 PM 159 Boyer Hall Tak W. Mak, Ph.D. Tumours and Tremors: How PTEN Regulation Underlies Both Department of Medical Biophysics, Ontario Cancer CenterUniversity of Toronto, Canada Tak W. Mak, Ph.D. Ming Guo, x67597 No 2005-11-10 4 PM 159 Boyer Hall Sandra L. Schmid, Ph.D. Dynamin's Dual Role in Clathrin-mediated Endocytosis Department of Cell Biology, The Scripps Research InstituteLa Jolla CA Sandra L. Schmid, Ph.D. Greg Payne, x63121 No 2005-11-17 4 PM 159 Boyer Hall Lorena S. Beese, Ph.D. Protein Prenyltransferases: From Structural Enzymology to Therapeutics Department of Biochemistry, Duke University Medical CenterDurham NC Lorena S. Beese, Ph.D. Fuyu Tamanoi, x67318 No 2005-12-01 4 PM 159 Boyer Hall Samuel Pfaff, Ph.D. Specification of Spinal Neuron Identity and the Control of Connectivity Gene Expression Laboratory, Salk Institute for Biological StudiesLa Jolla CA Samuel Pfaff, Ph.D. Ellen Carpenter, x63404 No 2005-12-08 4 PM 159 Boyer Hall Edward M. Levine, Ph.D. Molecular Control of Retinal Progenitor Cell Proliferation Department of Ophthalmology, University of UtahSalt Lake City Edward M. Levine, Ph.D. Evan Hsieh (Yang lab), x56992 No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall Kenneth R. Chien TBA Harvard Stem Cell InstituteHarvard Medical School Kenneth R. Chien Host: Yibin Wang, x65197 No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall Mike Thomashow, Ph.D. TBA Department of Crop and Soil ScienceMichigan State UniversityEast Lansing, Michigan Mike Thomashow, Ph.D. Chentao Lin No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-01 4 PM 159 Boyer Hall No 2006-01-12 4 PM 159 Boyer Hall Robert B. Darnell, M.D., Ph.D. RNA Binding Proteins and the Regulation of Neuronal Synaptic Plasticity Cancer Biology, The Rockefeller UniversityNew York, NY Robert B. Darnell, M.D., Ph.D. Doug Black x47644 No 2006-01-19 4 PM 159 Boyer Hall Saeed Tavazoie, Ph.D. Systematic Mapping of Phenotypic Traits to Genes Department of Molecular Biology, Lewis-Sigler Institute for Integrative GenomicsPrinceton University, New Jersey Saeed Tavazoie, Ph.D. Siavash Kurdistani x45194 No 2006-01-26 4 PM 159 Boyer Hall Bonnie L. Bassler, Ph.D. Tiny Conspiracies: Cell-to-Cell Communication in Bacteria Department of Molecular Biology, Princeton University, New Jersey Bonnie L. Bassler, Ph.D. Beth Lazazzera x44804 and Ann Hirsch68673 No 2006-02-02 4 PM 159 Boyer Hall Helen H. Hobbs, M.D. Genetic Architecture of Complex Traits: Lipoproteins and Atherosclerosis McDermott Center for Human Growth and Development, Center for Human Genetics UT Southwestern Medical Center, Dallas, TX Helen H. Hobbs, M.D. Steve Young x75220 No 2006-02-09 3 PM NRB 1st Fl Conf Rm Joseph L. Goldstein, M.D. The SREBP Pathway: How Genes Control Cholesterol and Vice Versa Department of Molecular Genetics, UT Southwestern Medical CenterDallas, TX *SIGMAN SYMPOSIUM - Special location* Joseph L. Goldstein, M.D. David Eisenberg x53754 NRB 1stFlr ConfRm No 2006-02-16 4 PM 159 Boyer Hall Junjie Chen, Ph.D. Cell Cycle Checkpoint Control and Tumorigenesis Department of Oncology, Mayo Clinic Cancer CenterMayo Clinic College of Medicine, Rochester, MN Junjie Chen, Ph.D. Mike Teitell x66754 No 2006-02-23 4 PM 159 Boyer Hall George B. Witman, Ph.D. A Tale of Two Tails: How Basic Research on the Chlamydomonas Flagellum is Leading to New Insights into Human Disease Department of Cell Biology, University of Massachusetts Medical School, Worcester George B. Witman, Ph.D. Kent Hill, x70546 No 2006-03-02 4 PM 159 Boyer Hall Amy Wagers, Ph.D. Tissue Specificity of Blood and Muscle Precursor Cells Department of Pathology, Section on Developmental & Stem BiologyJoslin Diabetes Center, Harvard Medical School, Boston, MA Amy Wagers, Ph.D. Carrie Miceli x66483 No 2006-03-09 4 PM 159 Boyer Hall Dale Dorsett, Ph.D. Sister Chromatid Cohesion and Long-range Gene Activation in Drosophila: A Model for Human Cornelia de Lange Syndrome Department of Biochemistry & Molecular Biology, St. Louis University School of Medicine, Missouri Dale Dorsett, Ph.D. Arnie Berk, x66298 No 2006-03-16 4 PM 159 Boyer Hall Michael Rosbash, Ph.D. Chromatin-RNP-Nuclear Pore Connections in Yeast Department of Biology, Brandeis University, Waltham, MA Michael Rosbash, Ph.D. Guillaume Chanfreau x54399 No 2006-04-06 4 PM 159 Boyer Hall Louis M. Kunkel, Ph.D. Muscular Dystrophy in Humans, Mice and Zebrafish Department of Genetics, Children's Hospital Harvard Medical School, Boston, MA Louis M. Kunkel, Ph.D. Stan Nelson x47981 No 2006-04-13 4 PM 159 Boyer Hall Iswar K. Hariharan, Ph.D. Genes that Restrict Growth and Cell Proliferationin Drosophila and Humans Department of Molecular & Cell Biology, UC Berkeley Iswar K. Hariharan, Ph.D. Utpal Banerjee, x65439 No 2006-04-19 4 PM 159 Boyer Hall Chris Somerville TBA Department of Biological SciencesStanford University Chris Somerville Chentao Lin, x69576 No 2006-04-20 4 PM 159 Boyer Hall Wei Gu, Ph.D. Modifying the Conventional View of p53 Activation Institute for Cancer Genetics, Columbia University, New York NY Wei Gu, Ph.D. William Yang, x72761 No 2006-04-27 4 PM 159 Boyer Hall Jen Sheen, Ph.D. Glucose Sensing and Signaling Network in Plants Department of Molecular Biology, Massachusetts General HospitalHarvard Medical School, Boston Jen Sheen, Ph.D. Elaine Tobin x57700 No 2006-05-04 4 PM 159 Boyer Hall Wah Chiu, Ph.D. Electron Cryomicroscopy of Biological Assemblies Department of Biochemistry & Molecular Biology, National Center for Macromolecular ImagingBaylor College of Medicine, Houston TX Wah Chiu, Ph.D. Lenny Rome x58680 No 2006-05-11 4 PM 159 Boyer Hall Angelika Amon, Ph.D. Control of Chromosome Segregation Center for Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge MA Angelika Amon, Ph.D. Arnie Berk x66298 No 2006-05-18 4 PM 159 Boyer Hall Vadim N. Gladyshev, Ph.D. Selenoproteome Department of Biochemistry, University of Nebraska, Lincoln Vadim N. Gladyshev, Ph.D. Sabeeha Merchant x58300 No 2006-05-25 4 PM 159 Boyer Hall Harry B. Gray, Ph.D. The Currents of Life: Electron Flow through Metalloproteins Division of Chemistry and Chemical Engineering, Beckman InstituteCalifornia Institute of Technology, Pasadena Harry B. Gray, Ph.D. Sabeeha Merchant x58300 No 2006-06-01 4 PM 159 Boyer Hall Vamsi K. Mootha, M.D. Genome-scale Approaches to Mitochondrial Biology Department of Systems Biology, Broad InstituteHarvard Medical School, Boston MA Vamsi K. Mootha, M.D. Siavash Kurdistani x45194 No 2006-06-08 4 PM 159 Boyer Hall Stephen J. King, Ph.D. Dynein and Dynactin: Two Components of a Molecular Motor Molecular Biology & Biochemistry, School of Biological Sciences, University of Missouri, Kansas City Stephen J. King, Ph.D. Rachelle Crosbie x42103 No 2006-09-28 4 PM 159 Boyer Hall Russell Debose-Boyd, Ph.D. Regulation of Cholesterol Synthesis Through Sterol-Accelerated Degradation of HMG CoA Reductase Department of Biophysics and Molecular GeneticsUniversity of Texas, Southwestern Russell Debose-Boyd, Ph.D. Stephen Young, x54934 No 2006-10-05 4 PM 159 Boyer Hall John T. Lis, Ph.D. Transcription Factor Recruitment, Dynamics, and Function in Living Cells and in Real Time Department of Molecular Biology & GeneticsCornell University, Ithaca, NY John T. Lis, Ph.D. Arnie Berk x66298 No 2006-10-12 4 PM 159 Boyer Hall Melissa J. Moore, Ph.D. An RNA Play in Two Acts: (1) A Novel Function for the Exon Junction Complex at Neuronal Synapses and (2) Degradation of Non-Functional Ribosomal RNAs in Budding Yeast Department of BiochemistryBrandeis Universityand Howard Hughes Medical Institute (HHMI) Melissa J. Moore, Ph.D. Doug Black, x47644 No 2006-10-19 4 PM 159 Boyer Hall David Schatz, Ph.D. Targeting and Spread of Mutations during Somatic Hypermutation Department of Immunology, Yale University School of Medicine, New Haven CT David Schatz, Ph.D. Arnie Berk x66298 No 2006-10-26 4 PM 159 Boyer Hall No seminar this week! No seminar this week! No 2006-11-02 4 PM 159 Boyer Hall Ruth Lehmann, Ph.D. Germ Cells Are Forever Department of Cell BiologyNew York University Medical Center Ruth Lehmann, Ph.D. Arnie Berk x66298 No 2006-11-09 4 PM 159 Boyer Hall Anne L. Calof, Ph.D. Regulation of Mammalian Neurogenesis Department of Anatomy & Neurobiology, Developmental Biology Center, UC Irvine Anne L. Calof, Ph.D. Karen Lyons, x55480 No 2006-11-16 4 PM 159 Boyer Hall Gerald R. Crabtree, M.D.,Ph.D. Subunit Exchange Within Chromatin Remodeling Complexes Underlies the Transition from Stem Cells to Neurons Department of Developmental BiologyStanford University Gerald R. Crabtree, M.D.,Ph.D. Arnie Berk x66298 No 2006-11-30 4 PM 159 Boyer Hall Eddy Rubin, M.D., Ph.D. Extreme Comparative Genomics: Microbes to Neanderthals Genome Sciences DepartmentLawrence Berkeley National Laboratory (LBNL) Eddy Rubin, M.D., Ph.D. Stephen Young, x54934 No 2006-12-07 4 PM 159 Boyer Hall Joshua M. Kaplan, Ph.D. Mechanisms Regulating Synaptic Transmission in C. elegans Department of Molecular Biology, Massachusetts General Hospital, Harvard University Joshua M. Kaplan, Ph.D. Greg Payne x63121 No 2006-12-14 4 PM 159 Boyer Hall Claude Desplan, Ph.D. Detection and Processing of Color Information in Drosophila Department of BiologyNew York University Claude Desplan, Ph.D. Larry Zipursky, x52834 No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-01 4 PM 159 Boyer Hall Frank Rauscher, III, Ph.D. TBA The Wistar Institute, Philadelphia, PA Frank Rauscher, III, Ph.D. Host: Arnie Berk, x66298Molecular Biology Institute No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-01 4 PM 159 Boyer Hall Scott Hammond, Ph.D. TBA Carolina Cardiovascular Biology CenterUniversity of North Carolina at Chapel Hill Scott Hammond, Ph.D. Host: Feng Guo, x64576Molecular Biology Institute No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-01 4 PM 159 Boyer Hall No 2007-01-11 4 PM 159 Boyer Hall David P. Giedroc, Ph.D. TBA Department of Biochemistry & BiophysicsTexas A & M University David P. Giedroc, Ph.D. Sabeeha Merchant, x58300 No 2007-01-18 4 PM 159 Boyer Hall David R. Cox, M.D., Ph.D. Human Genetic Variation and Common Disease Perlagen Sciences David R. Cox, M.D., Ph.D. Stephen Young, x54934 No 2007-01-24 4 PM 159 Boyer Hall George Weinstock, Ph.D. TBA Departments of Molecular and Human Genetics and Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX George Weinstock, Ph.D. Host: Ann Hirsch, x68673Molecular Biology Institute No 2007-02-01 4 PM 159 Boyer Hall Andrew P. McMahon, Ph.D. TBA Department of Molecular and Cellular BiologyHarvard University Andrew P. McMahon, Ph.D. Karen Lyons, x55480 No 2007-02-08 4 PM 159 Boyer Hall Marc Tessier-Lavigne, Ph.D. Wiring the Brain and Vasculature: Common Mechanisms, Common Molecules Genentech Marc Tessier-Lavigne, Ph.D. Alvaro Sagasti, x66147 No 2007-02-15 4 PM 159 Boyer Hall A. Thomas Look, M.D. The Emerging Genetics of T-Cell Acute Lymphoblastic Leukemia Department of Pediatric OncologyHarvard Medical School A. Thomas Look, M.D. Shuo Lin, x74970 No 2007-02-22 4 PM 159 Boyer Hall Andrew S. Belmont, M.D., Ph.D. Large-Scale Chromatin Structure and Dynamics Departments of Cell & Structural Biology and BiophysicsUniversity of Illinois, Urbana-Champaign Andrew S. Belmont, M.D., Ph.D. Arnie Berk, x66298 No 2007-03-01 4 PM 159 Boyer Hall Richard J. Youle, Ph.D. Apoptosis, Bcl-2 Family Proteins and Mitochondria in Apoptosis National Institutes of Health (NIH) Richard J. Youle, Ph.D. Alex van der Bliek, x59779 No 2007-03-08 4 PM 159 Boyer Hall Weimin Zhong, Ph.D. Mechanisms of Stem Cell Homeostasis Department of Molecular, Cellular and Developmental BiologyYale University Weimin Zhong, Ph.D. William Yang, x72761 Host: William Yang, x72761 No 2007-03-15 4 PM 159 Boyer Hall Kenneth R. Chien, M.D., Ph.D. "Master Islet1+ Cardiovascular Progenitors: Toward HumanModels of Cardiovascular Disease" The Stem Cell Institute,MGH Cardiovascular Research Center, Harvard Kenneth R. Chien, M.D., Ph.D. Host: Yibin Wang, x65197 No 2007-03-15 4:00 PM Boyer 159 Kenneth R. Chien, M.D., Ph.D. "Master Islet1+ Cardiovascular Progenitors: Toward HumanModels of Cardiovascular Disease" MGH Cardiovascular Research CenterDepaartment of Cell Biology, HMSHarvard Stem Cell InstituteMassachusettes General Hospital Kenneth R. Chien, M.D., Ph.D. Host:Yibin Wang, x65197Molecular Biology Institute No 2007-03-15 4:00 PM Boyer 159 Kenneth R. Chien, M.D., Ph.D. "Master Islet1+ Cardiovascular Progenitors: Toward HumanModels of Cardiovascular Disease" MGH Cardiovascular Research CenterDepaartment of Cell Biology, HMSHarvard Stem Cell InstituteMassachusettes General Hospital Kenneth R. Chien, M.D., Ph.D. Host:Yibin Wang, x65197Co-Sponsored by the Molecular Biology Institute and the Division of Molecular Medicine No 2007-03-15 4:00 PM Boyer 159 Kenneth R. Chien, M.D., Ph.D. "Master Islet1+ Cardiovascular Progenitors: Toward HumanModels of Cardiovascular Disease" MGH Cardiovascular Research CenterDepaartment of Cell Biology, HMSHarvard Stem Cell InstituteMassachusettes General Hospital Kenneth R. Chien, M.D., Ph.D. Host:Yibin Wang, x65197Co-Sponsored by the Molecular Biology Instituteand the Division of Molecular Medicine No 2007-03-21 4 PM 159 Boyer Hall Anne Ephrussi, Ph.D. Assembly of an mRNP Complex for Intracellular mRNA Transport and Translational Control European Molecular Biology Laboratory Anne Ephrussi, Ph.D. Doug Black, x47644 Host: Doug Black, x47644 No 2007-03-29 4:00 PM Boyer 159 *****NO SEMINAR TODAY***** The MBI Thursday Seminars will resume Thursday, April 12, 2007 *****NO SEMINAR TODAY***** No 2007-04-05 4:00 PM Boyer 159 *****NO SEMINAR TODAY***** The MBI Thursday Seminars will resumeThursday, April 12, 2007 *****NO SEMINAR TODAY***** No 2007-04-12 4 PM 159 Boyer Hall Ann Marie Pendergast, Ph.D. Regulation of Intercellular Conversations by Abl Kinases and Actin Modulators Department of Pharmacology & Cancer BiologyDuke University Medical Center Ann Marie Pendergast, Ph.D. John Colicelli, x61400 No 2007-04-12 4:00 PM Boyer 159 Ann Marie Pendergast, Ph.D. "Regulation of Intercellular Conversations byAbl Kinases and Actin Modulators" Department of Pharmacology & Cancer BiologyDuke University Medical Center Ann Marie Pendergast, Ph.D. Host: John Colicelli, x61400Molecular Biology Institute No 2007-04-19 4 PM 159 Boyer Hall Chris Somerville, Ph.D. Genetic Dissection of Cell Wall Synthesis in Arabidopsis Department of Plant Biology, Carnegie Institutionand Department of Biological Sciences, Stanford Chris Somerville, Ph.D. Chentao Lin, x69576 No 2007-04-26 4:00 PM Boyer 159 Luisa Iruela-Arispe, Ph.D. "VEGF Signaling and Vascular Function:We Though We Knew It All, But Then..." Department of Molecular, Cell, and Developmental BiologyMember, Molecular Biology Institute, UCLA Luisa Iruela-Arispe, Ph.D. Host: Jau-nian Chen, x64513Molecular Biology Insitute No 2007-05-03 4:00 PM Boyer 159 William Snell, Ph.D. Cilium-Generated Signaling and Cell-Cell Fusion During Fertilization in Chlamydomonas Department of Cell BiologyGraduate School of Biomedical SciencesSouthwestern Medical School, Dallas, Texas William Snell, Ph.D. Host: Kent Hill, x70546Molecular Biology Institute No 2007-05-03 4:00 PM Boyer 159 CANCEL William Snell, Ph.D. Cilium-generated Signaling and Cell-CellFusion during Fertilization in Chlamydomonas Graduate School of Biomedical SciencesUniversity of Texas Southwestern Medical SchoolDallas, Texas CANCEL William Snell, Ph.D. Host: Kent Hill, x70546Molecular Biology Institute No 2007-05-10 4 PM 159 Boyer Hall Barry Paw, M.D., Ph.D. The Role of the Mitochondrial Solute Transporter, Mitoferrin, in Vertebrate Erythropoiesis Departments of Hematology/Oncology, Pediatric Oncology, and MedicineHarvard Medical School Barry Paw, M.D., Ph.D. Guillaume Chanfreau, x54399 No 2007-05-17 4 PM 159 Boyer Hall Hong Ma, Ph.D. Cell-Cell Signaling and Transcriptional Networks Department of Biology,Penn State University Hong Ma, Ph.D. Host: Chentao Lin, x69576 No 2007-05-24 4 PM 159 Boyer Hall John Blenis, Ph.D. Ras, P13-Kinase & mTOR:Signal Integration and Cell Growth Department of Cell BiologyHarvard Medical School John Blenis, Ph.D. John Colicelli, x61400 Host: John Colicelli, x61400 No 2007-05-31 4 PM 159 Boyer Hall Yunde Zhao, Ph.D. Control of Auxin Dynamics in Arabidopsis Organogenesis Department of Biology, UCSD Yunde Zhao, Ph.D. Host: Chentao Lin, x69576Molecular Biology Institute No 2007-06-07 4 PM 159 Boyer Hall John Mekalanos, Ph.D. Vibrio Cholerae Type III and VI Secretion Systems Department of Microbiology and Molecular GeneticsHarvard School of Medicine John Mekalanos, Ph.D. Host: Wen Shi, x58356 No 2007-09-27 4:00 PM Boyer 159 Enamul Huq, Ph.D. Light Signal Transduction in Plants Molecular Cell and DevelopmentalBiology at the University of Texas at Austin Enamul Huq, Ph.D. Host: Chentao Lin, x69576Molecular Biology Institute No 2007-10-04 4 PM 159 Boyer Hall Shu-ou Shan A Tale of Two GTPases in Co-Translational Protein Transport Division of Chemistry and Chemical Engineering, CALTECH Shu-ou Shan Host: Leonard Rome, x58680Molecular Biology Institute No 2007-10-11 4 PM 159 Boyer Hall Marnie Halpern, Ph.D. Left-Right Asymmetry in the Zebrafish Forebrain Department of EmbryologyCarnegie Institute of Washington Marnie Halpern, Ph.D. Host: Alvaro Sagasti, x66147Molecular Biology Institute No 2007-10-18 4 PM 159 Boyer Hall David Russell, Ph.D. Cholesterol Turnover in the Brain Division of Molecular GeneticsUniversity of Texas Southwestern Medical CenterDallas, TX David Russell, Ph.D. Host: Stephen Young, x54934Molecular Biology Institute No 2007-10-25 4 PM 159 Boyer Hall Susan Marqusee, Ph.D. Experimental Tools to Investigate andManipulate the Protein Energy Landscape Department of Molecular &Cell Biology, UC Berkeley Susan Marqusee, Ph.D. Host: Todd Yeates, x64866Molecular Biology Institute No 2007-11-01 4:00 PM Boyer 159 Carol V. Robinson, Ph.D. Protein Complexes from Cells to the Gas Phase Division of Mass SpectrometryDepartment of ChemistryUniversity of Cambridge, United Kingdom Carol V. Robinson, Ph.D. Host: David Eisenberg, x53754 and Greg Payne, x63121Molecular Biology Institute and theBiological Chemistry Distinguished Speaker Series No 2007-11-08 4:00 PM Boyer 159 Mark Estelle, Ph.D. Genetic and Biochemical Studies of the AuxinReceptor Reveal a Novel Mechanism of Hormone Perception Department of Plant DevelopmentalBiology, Indiana University Mark Estelle, Ph.D. Elaine Tobin, x57700Molecular Biology Institute No 2007-11-15 4 PM 159 Boyer Hall Xiaojiang Chen, Ph.D. Structures and Function of Hexameric Helicases in DNA Replication: The Same Type of Ring with Different Fashion Programs in Biomedical and Biological SciencesUniversity of Southern California Xiaojiang Chen, Ph.D. Host: Feng Guo, x64576Molecular Biology Institute No 2007-11-29 4 PM 159 Boyer Hall Joachim Herz, M.D. ApoE Receptors: Universal Modulators of Cellular Signal Transduction Biophysics and Molecular Genetics, University of TexasSouthwestern Medical Center Joachim Herz, M.D. Host: Stephen Young, x54934Molecular Biology Institute No 2007-12-06 4:00 PM Boyer 159 Margaret T. Fuller, Ph.D. Regulation of Self-Renewal, Proliferation, and Differentiation in a Stem Cell Lineage Department of Developmental Biologyand Genetics, Stanford School of Medicine Margaret T. Fuller, Ph.D. Utpal Banerjee, x65439Molecular Biology Institute No 2008-01-10 4:00 PM Boyer 159 Alexander Tzagoloff, Ph.D. Assembly of the MitochondrialATPase in Yeast Department of Biological Sciences, Columbia University, New York, NY Alexander Tzagoloff, Ph.D. Host: Carla Koehler, x44834Molecular Biology Institute No 2008-01-17 4 PM 159 Boyer Hall Frank Rauscher, III, Ph.D. New Insights into Combinatorial Recognition ofHistaone Modifications: Role of Sumoylation of Bromodomains The Wistar Institute, Philadelphia, PA Frank Rauscher, III, Ph.D. Host: Arnold Berk, x66298Molecular Biology Institute No 2008-01-24 4 PM 159 Boyer Hall George Weinstock, Ph.D. New Direction in Genomics fromMicrobe to Man Departments of Molecular & Human Genetics and MolecularVirology and Microbiology, Baylor College of Medicine, Houston, TX George Weinstock, Ph.D. Host: Ann Hirsch, x68673Molecular Biology Institute No 2008-01-31 4 PM 159 Boyer Hall Roland Riek, Ph.D. Structural Studies of Protein Aggregates The Salk Institute for Biological Studies and the Swiss Federal Institute of Technology (ETH), Zurich, Switzerland Roland Riek, Ph.D. Host: David Eisenberg, x53754Molecular Biology Institute No 2008-02-14 4 PM 159 Boyer Hall Robert Kingston, Ph.D. Applying New Technologies to UnravelRegulation and Packaging of the Genome Molecular Biology, Department of Genetics,Harvard Medical School, Cambridge, MA Robert Kingston, Ph.D. Host: Kathrin Plath, x68688Molecular Biology Institute No 2008-02-21 4 PM 159 Boyer Hall Johannes Walter, Ph.D. PCNA-Dependent Cdt1 Destruction in S Phase:a New Paradigm for Spatial and TemporalRegulation of Proteolysis? Department of Biological Chemistry and Molecular PharmacologyHarvard Medical School, Boston, MA Johannes Walter, Ph.D. Host: James Wohlschlegel, x47955Molecular Biology Institute No 2008-02-28 4 PM 159 Boyer Hall Brian Kennedy, Ph.D. Aging Biology: The Long and the Short of It Department of Biochemistry, University of Washington, Seattle Brian Kennedy, Ph.D. Host: Stephen Young, x54934Molecular Biology Institute No 2008-03-06 4 PM 159 Boyer Hall Janet Shaw, Ph.D. Membrane Remodeling and Transport Machines: Lessons from the Mitochondrion Department of Biochemistry,University of Utah, Salt Lake City, UT Janet Shaw, Ph.D. Host: Greg Payne, x63121Molecular Biology Institute No 2008-03-13 4 PM 159 Boyer Hall Ira Mellman, Ph.D. The Cell Biology of Dendritic Cell Function Vice President Research, Oncology Genentech, San Francisco, CA Ira Mellman, Ph.D. Host: Kelsey Martin, x49507Molecular Biology Institute No 2008-04-03 4 PM 159 Boyer Hall Norman Pace, Ph.D. Structure and Catalytic Functionof RNase P, a Ribozyme Molecular, Cellular and Developmental Biology,University of Colorado, Boulder, CO Norman Pace, Ph.D. Host: Guillaume Chanfreau, x54399Molecular Biology Institute No 2008-04-10 4 PM 159 Boyer Hall Tom Rapoport, Ph.D. How the Endoplasmic Reticulum (ER) Gets into Shape Department of Cell Biology, Harvard, Cambridge, MA Tom Rapoport, Ph.D. Host: Kathrin Plath, x68688Molecular Biology Institute No 2008-04-17 4 PM 159 Boyer Hall Jill Banfield, Ph.D. Microbial Community Genomics Earth and Planetary Sciences, UC Berkeley Jill Banfield, Ph.D. Host: Jim Lake, x52546Molecular Biology Institute No 2008-04-24 4 PM 159 Boyer Hall Jef Boeke, Ph.D., D. Sc. Natural and Synthetic Mammalian Retrotransposons Department of Molecular Biology and Genetics,Department of Oncology, The Johns HopkinsUniversity School of Medicine, Baltimore, MD Jef Boeke, Ph.D., D. Sc. Host: John Colicelli, 61400Molecular Biology Institute No 2008-05-01 4 PM 159 Boyer Hall Alan Grossman, Ph.D. Regulation of Horizontal Gene Transfer and Recognition of Self in Bacillus Subtilis Department of Biology, Massachussetts Institute of Technology (MIT) Alan Grossman, Ph.D. Host: Beth Lazazzera, x44804Molecular Biology Institute No 2008-05-08 4 PM 159 Boyer Hall Joanne Chory, Ph.D. Dissection of Growth Control Networks in Plants The Plant Molecular and Cellular Biology Laboratory, The Salk Institute, La Jolla, CA Joanne Chory, Ph.D. Host: Elaine Tobin, x57700Molecular Biology Institute No 2008-05-15 4 PM 159 Boyer Hall No Seminar No Seminar No 2008-05-22 4 PM 159 Boyer Hall Mark Hochstrasser, Ph.D. Ubiquitin-Proteasome System Function at the ER and Inner Nuclear Envelope Molecular Biophysics and BiochemistryYale University, New Haven, Connecticut Mark Hochstrasser, Ph.D. Host: Greg Payne, x63121Molecular Biology Institute No 2008-05-29 4 PM 159 Boyer Hall Henry Kronenberg, M.D., Ph.D. PTH/PTHrP Receptor Signaling: Builder and Destroyer of Bone Departments of Endocrinology and Medicine, MassachusettsGeneral Hospital and Harvard Medical School Henry Kronenberg, M.D., Ph.D. Host: Karen Lyons, x55480Molecular Biology Institute No 2008-06-05 4 PM 159 Boyer Hall Steven L. Mayo, Ph.D. Recent Advances in Computational Protein Design: Enzymes and Protein Libraries Vice Provost (Research) and Bren Professor ofBiology and Chemistry, CalTech Steven L. Mayo, Ph.D. Host: Diana AzurdiaMolecular Biology Institute and Graduate Students for Diversity in Chemistry No 2008-09-25 4 PM 159 Boyer Hall Scott Hammond, Ph.D. MicroRNAs in Development and Disease Carolina Cardiovascular Biology CenterUniversity of North Carolina at Chapel Hill Scott Hammond, Ph.D. Host: Feng Guo, x64576Molecular Biology Institute No 2008-10-02 4 PM 159 Boyer Hall Eloy Rodriguez, Ph.D. The Genesis and Organic Chemistry of Natural Medicines Department of Plant Biology, Cornell University, Ithaca, NY Eloy Rodriguez, Ph.D. Host: Diana Azurdia, dianazurdia@gmail.comJointly Sponsored by the Molecular Biology Instituteand the Graduate Students for Diversity in Chemistry No 2008-10-09 4 PM 159 Boyer Hall Robert F. Siliciano, M.D., Ph.D. HIV Persistence in Patients on HAART: Re-evaluating Prospects for Eradication Department of Medicine/Infectious Diseases,Howard Hughes Medical Institute at The Johns HopkinsUniversity School of Medicine, Baltimore, MD Robert F. Siliciano, M.D., Ph.D. Host: Steve Young, x54934Molecular Biology Institute No 2008-10-16 4 PM 159 Boyer Hall Michael White, Ph.D. Targeting Conditional Dependencies in Tumorigenic Regulatory Networks Department of Cell Biology, University of Texas SouthwesternGraduate School of Biomedical Sciences, Dallas Michael White, Ph.D. Fuyu Tamanoi, x67318 Molecular Biology Institute No 2008-10-23 4 PM 159 Boyer Hall Jeff Dangl, Ph.D. The Plant Immune System Department of Cell and Developmental Biology,University of North Carolina, Chapel Hill Jeff Dangl, Ph.D. Hosts: Jeffery F. Miller, x67926 and Sabeeha Merchant, x58300Molecular Biology Institute No 2008-10-30 4 PM 159 Boyer Hall Ming Lei, Ph.D. Capping the End: Structure andFunction of Telomere Proteins Department of Biological Chemistry, University of Michigan, Ann Arbor Ming Lei, Ph.D. Host: Feng Guo, x64576Molecular Biology Institute No 2008-11-06 4 PM 159 Boyer Hall Marius Clore, M.D., Ph.D. Visualizing Lowly-Populated Regions of the Free Energy Landscape ofMacromolecules and their Complexes by Paramagnetic NMR Protein Nuclear Magnetic Resonance Spectroscopy Section,Laboratory of Chemical Physics, NIDDK, NIH, Bethesda, MD Marius Clore, M.D., Ph.D. Host: Robert Clubb, x62334Molecular Biology Institute No 2008-11-13 4 PM 159 Boyer Hall Jeffrey L. Wrana, Ph.D. Polarity Pathways Illuminated by High Throughput Biology Department of Molecular Biology and Cancerat the Samuel Lunenfeld Research Institute, Mount Sinai Hospital,Department of Medical Genetics and Microbiology at the University of Toronto, Canada Jeffrey L. Wrana, Ph.D. Host: Gerry Weinmaster, x69446Molecular Biology Institute No 2008-11-20 4 PM 159 Boyer Hall Ursula Jakob, Ph.D. Oxidative Stress and Redox Regulation - Turning Lemons into Lemonade Department of Molecular, Cellular, & Developmental Biology,University of Michigan, Ann Arbor Ursula Jakob, Ph.D. Host: Carla Koehler, x44834Molecular Biology Institute No 2008-12-04 4 PM 159 Boyer Hall Robert T. Sauer, Ph.D. Machines of Protein Destruction Department of Biology, MassachusettsInstitute of Technology, Cambridge Robert T. Sauer, Ph.D. Host: Jim Bowie, x64747Molecular Biology Institute No 2009-01-01 4 PM 159 Boyer Hall David Morgan, Ph.D. TBA Department of Physiology, UC San Francisco David Morgan, Ph.D. Host: Arnold Berk, x66298Molecular Biology Institute No 2009-01-08 4 PM 159 Boyer Hall Robert Tycko, Ph.D. Molecular Structure of Amyloid and Prion Fibrils:Insights from Solid State Nuclear Magnetic Resonance Laboratory of Chemical Physics, National Institute of Diabetes and Digestive& Kidney Diseases, National Institute of Health, Bethesda, MD Robert Tycko, Ph.D. Host: David Eisenberg, x53754Molecular Biology Institute No 2009-01-15 4 PM Boyer 159 Michael Elowitz, Ph.D. Dynamics and Coordination at the Single-Cell Level Division of Biology, California Institute of Technology, Pasadena, CA Michael Elowitz, Ph.D. Host: Beth Lazazzera, x44804Molecular Biology Institute No 2009-01-22 4 PM NRB Auditorium 2009 DAVID S. SIGMAN MEMORIAL LECTURE & SYMPOSIUMJoAnne Stubbe, Ph.D. Ironing Out Ribonucleotide ReductasePLEASE NOTE THAT THIS SYMPOSIUM IS IN THE NRB AUDITORIUM Departments of Chemmistry and Biology,Massachusetts Institute of Technology, Cambridge 2009 DAVID S. SIGMAN MEMORIAL LECTURE & SYMPOSIUMJoAnne Stubbe, Ph.D. Sabeeha Merchant, x58300 Molecular Biology Institute No 2009-01-29 4 PM 159 Boyer Hall Jodi Nunnari, Ph.D. The Machines that Divide and Fuse Mitochondria Department of Molecular and Cellular Biology, UC Davis Jodi Nunnari, Ph.D. Host: Carla Koehler, x44834Molecular Biology Institute No 2009-02-05 4 PM 159 Boyer Hall Neil Segil, Ph.D. Development and Regeneration of the Inner Ear: Coordinating CellCycle and Differentiation–Constraining Notch Signaling Section on Cell Cycle, Growth and Differentiation, House Ear Institute; Laboratory of Developmental Biology, Gonda Department of Cellular and Molecular Biology, UCLA Neil Segil, Ph.D. Host: Bennett Novitch, x49339Molecular Biology Institue No 2009-02-12 4 PM 159 Boyer Hall Susan Gottesman, Ph.D. Small RNA Regulators and the Bacterial Response to Stress Biochemical Genetics Section, Laboratory of Molecular BiologyNational Cancer Institute, NIH, Bethesda MD Susan Gottesman, Ph.D. Host: Rob Gunsalus, x68201Molecular Biology Institute No 2009-02-19 4 PM 159 Boyer Hall Stephen Blacklow, M.D., Ph.D. Mechanistic Insights into Normall and Pathogenic Notch Signalilng Department of Pathology, Brigham and Women's Hospital,Division of Medical Sciences, Harvard University, Boston, MA Stephen Blacklow, M.D., Ph.D. Host: James Wohlschlegel, x47955Molecular Biology Institute No 2009-02-26 4 PM 159 Boyer Hall Janice Fischer, Ph.D. A Puzzling Role for Endocytosis in Notch Signaling Department of Molecular, Cell, and Developmental Biology,University of Texas, Austin Janice Fischer, Ph.D. Host: Gerry Weinmaster, x69446Molecular Biology Institute No 2009-03-05 4 PM 159 Boyer Hall Lewis C. Cantley, Ph.D. PI 3-Kinase Signaling Networks Department of Systems Biology, Division of Signal Transduction,BIH Harvard Institutes of Medicine, Boston, MA Lewis C. Cantley, Ph.D. Host: Mike Teitell, x66754Molecular Biology Institute No 2009-03-10 4 PM 159 Boyer Hall Gary Pielak, Ph.D. TBA Department of Chemistry, University of North Carolina at Chapel Hill Gary Pielak, Ph.D. Host: Gerry Weinmaster, x69446Molecular Biology Institute No 2009-03-12 4 PM 159 Boyer Hall Katie Peichel, Ph.D. Sex, Spines and Videotape: Genetics of ReproductiveIsolation in Sticklebacks Human Biology Division, Fred HutchinsonCancer Research Center, Seattle, WA Katie Peichel, Ph.D. Host: Alvaro Sagasti, x66147Molecular Biology Institute No 2009-04-02 4 PM 159 Boyer Hall H. M. Ottoline Leyser, Ph.D. Hormones, Shoot Branching Control and Developmental Plasticity Department of Biology, University of York, United Kingdom H. M. Ottoline Leyser, Ph.D. Host: Geraldine Weinmaster, x69446Molecular Biology Institute No 2009-04-16 4 PM 159 Boyer Hall Anna M. Pyle, Ph.D. Group II Intron Structure and Function: The AccidentalArchitects of Biological Diversity Department of Molecular Biophysics and Biochemistry,Yale University, New Haven, CT Anna M. Pyle, Ph.D. Host: Juli Feigon, x66922Molecular Biology Institute No 2009-04-23 4 PM 159 Boyer Hall CANCELLEDMannie Liscum, Ph.D. Musings and Cogitations on Phototropic Signaling Department of Biological Sciences, University of Missouri, Columbia CANCELLEDMannie Liscum, Ph.D. Host: Chentao Lin, x69576Molecular Biololgy Institute No 2009-04-30 4 PM 159 Boyer Hall Richard Caprioli, Ph.D. Molecular Profiling and Imaging of Tissues by Mass Spectrometry:Assessing Spatial and Temporal Factors Department of Biochemistry, Mass Spectrometry Research Center,Vanderbilt-Ingram Cancer Center, Nashville, TN Richard Caprioli, Ph.D. Host: Joseph Loo, x47023Molecular Biology Institute No 2009-05-06 4 PM 159 Boyer Hall Michael F. Thomashow, Ph.D. TBA Department of Molecular Genetics, MSU-DOE Plant Research Laboratory,Michigan State University, East Lansing Michael F. Thomashow, Ph.D. Host: Chentao Lin, x69576 No 2009-05-07 4 PM 159 Boyer Hall William Snell, Ph.D. Cilium-generated Signaling, Flagellar Length Control,and Gamete Fusion in the Green Alga Chlamydomonas Department of Cell Biology, University of TexasSouthwestern Medical Center, Dallas William Snell, Ph.D. Host: Kent Hill, x70546Molecular Biology Institute No 2009-05-14 4 PM 159 Boyer Hall Sarah Bray, Ph.D. Decoding the Notch Signal Department of Physiology, Development and Neuroscience,University of Cambridge, United Kingdom Sarah Bray, Ph.D. Host: Geraldine Weinmaster, x69446Molecular Biology Institute No 2009-05-21 4 PM 159 Boyer Hall Arnie Berk, M.D. Conversion of Differentiated Cells to Replicating Stem Cells byAdenovirus e1a Relocalization of RB and CBP Family Chromatin Modifying Proteins Department of Microbiology, Immunology, and Molecular Genetics, UCLA;Member, Molecular Biology Institute Arnie Berk, M.D. Molecular Biology Institute No 2009-05-28 4 PM 159 Boyer Hall Dyann Wirth, Ph.D. Genetic Diversity in Plasmodium Falciparum: Insights into Parasite Biology Department of Immunology and Infectious Diseases,Harvard School of Public Health, Cambridge, MA Dyann Wirth, Ph.D. Host: Patricia Johnson, x54870Molecular Biology Institute No 2009-06-04 4 PM 159 Boyer Hall Ranjan Sen, Ph.D. Regulation of Immunoglobulin Heavy Chain Gene Transcription and Recombination Laboratory of Cellular and Molecular Biology and Gene RegulationSection, National Institute on Aging Biomedical Research Center, Baltimore, MD Ranjan Sen, Ph.D. Host: Stphen Smale, x64777Molecular Biology Institute No 2009-09-24 4 PM 159 Boyer Hall *SPECIAL SEMINAR*Juli Feigon, Ph.D. A Tail of Two Pseudoknots: Structure and Dynamics ofTelomerase and Riboswitch RNA Department of Chemistry and Biochemistry, UCLA; Member, Molecular Biology Institute *SPECIAL SEMINAR*Juli Feigon, Ph.D. Host: Richard Dickerson, x55864 No 2009-10-01 4 PM 159 Boyer Hall NO MBI THURSDAY SEMINAR TODAYSERIES RESUMES NEXT WEEK ON OCT 8, 2009 NO MBI THURSDAY SEMINAR TODAYSERIES RESUMES NEXT WEEK ON OCT 8, 2009 No 2009-10-08 4 PM 159 Boyer Hall Stacey Harmer, Ph.D. Timing is Everything: the Plant Clock and its Outputs Department of Plant Biology, UC Davis Stacey Harmer, Ph.D. Host: Elaine Tobin, x57700 No 2009-10-15 4 PM 159 Boyer Hall R. Scott Hawley, Ph.D. The Molecular Genetics of Meiosis Stowers Institute for Medical Research, Kansas City, MO R. Scott Hawley, Ph.D. Host: MBIDP Graduate Students, e-mail:KTurlo@UCLA.edu No 2009-10-22 4 PM 159 Boyer Hall Xiang-Dong Fu, Ph.D. Reprogramming the Androgen Receptor in Prostate Cancer Department of Cellular & Molecular Medicine, UC San Diego Xiang-Dong Fu, Ph.D. Host: Xinshu (Grace) Xiao, x66522 No 2009-10-29 4 PM 159 Boyer Hall Hal Dietz, M.D. Marfan Syndrome and Related Disorders: From Molecules to Medicines Department of Pediatric Cardiology, Johns Hopkins UniversitySchool of Medicine, Baltimore, MD Hal Dietz, M.D. Host: Steve Young, x54934 No 2009-11-05 4 PM 159 Boyer Hall Ruslan Aphasizhev, Ph.D. RNA Processing in Trypanosome Mitochondria Department of Microbiology and Molecular Genetics, UC Irvine School of Medicine Ruslan Aphasizhev, Ph.D. Host: Larry Simpson, x54215 No 2009-11-12 4 PM 159 Boyer Hall John Yates, III, Ph.D. Driving Biological Discovery Using Quantitative Proteomics Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA John Yates, III, Ph.D. Host: Jing Huang, x54329 and James Wohlschlegel, x47955 No 2009-11-19 4 PM 159 Boyer Hall Nicholas Katsanis, Ph.D. The Ciliopathies: Modeling Human Genetic Disease Architecture Departments of Ophthalmology, Molecular Biology and Genetics,Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD Nicholas Katsanis, Ph.D. Host: Kent Hill, x70546 No 2009-12-03 4 PM 159 Boyer Hall John L. Spudich, Ph.D. Microbial Rhodopsins: Receptors, Channels, and Pumps from a Single Design Department of Biochemistry and Molecular Biology, University of Texas, Houston John L. Spudich, Ph.D. James Bowie, x64747 No 2009-12-10 4 PM 159 Boyer Hall James Berger, Ph.D. Catching a Motor in the Act: Molecular Basis for HexamericHelicase Translocation and Polarity Department of Biochemistry and Molecular Biology, UC Berkeley James Berger, Ph.D. Host: Reid Johnson, x57800 No 2010-01-07 4 PM 159 Boyer Hall Sheena Radford, Ph.D. To Fold or Not to Fold: How Well Evolved is Nature’s Folding Code? Astbury Centre for Structural Molecular Biology, University of Leeds, United Kingdom Sheena Radford, Ph.D. Host: David Eisenberg, x53754 No 2010-01-21 4 PM 159 Boyer Hall Greg Barton, Ph.D. TBA Division of Immunology and Pathogenesis, Department ofMolecular and Cell Biology, UC Berkeley Greg Barton, Ph.D. Host: Stephen Smale, x64777 No 2010-01-28 4 PM 159 Boyer Hall David Morgan, Ph.D. TBA Department of Physiology, UC San Francisco David Morgan, Ph.D. Host: Arnie Berk, x66298 No 2010-02-04 4 PM 159 Boyer Hall Peter Baumann, Ph.D. TBA Stowers Institute for Medical Research, Kansas City, MO Peter Baumann, Ph.D. Host: Feng Guo, x64576 No 2010-02-11 4 PM 159 Boyer Hall Ron David, M.D. TBA Departments of Medicine and Cell Biology, New York University, New York Ron David, M.D. Host: Yibin Wang, x65197 No 2010-02-18 4 PM 159 Boyer Hall Dimitri Krainc, M.D., Ph.D. TBA Department of Neurology, Harvard Medical School,Massachusetts General Hospital, Boston Dimitri Krainc, M.D., Ph.D. Host: William Yang, x72761 No 2010-02-25 4 PM 159 Boyer Hall Sir David Sherratt, Ph.D. TBA Department of Biochemistry, University of Oxford, England Sir David Sherratt, Ph.D. Host: David Eisenberg, x53754 No 2010-03-11 4 PM 159 Boyer Hall Gary Pielak, Ph.D. TBA Department of Chemistry, University of North Carolina at Chapel Hill Gary Pielak, Ph.D. Host: Gerry Weinmaster, x69446 No 2010-04-01 4 PM 159 Boyer Hall Pamela Schwartzberg, M.D., Ph.D. TBA Genetic Disease Research Branch, National Human Genome Research Institute,National Institute of Health, Bethesda, MD Pamela Schwartzberg, M.D., Ph.D. Host: John Colicelli, x51251 No 2010-04-08 4 PM 159 Boyer Hall Ben Barres, M.D., Ph.D. TBA Neurobiology and Developmental Biology, Stanford University, Palo Alto, CA Ben Barres, M.D., Ph.D. Hosts: Gerry Weinmaster, x69446 and Kelsey Martin, x49507 No 2010-04-15 4 PM 159 Boyer Hall Michael P. Rout, Ph.D. TBA Laboratory of Cellular and Structual Biology, The Rockefeller University, New York, NY Michael P. Rout, Ph.D. Host: Carla Koehler, x44834 and Dev Majumdar, e-mail:devdoot@ucla.edu No 2010-04-22 4 PM 159 Boyer Hall Andreas Matouschek, Ph.D. TBA Department of Biochemistry Molecular Biology, and Cell Biology,Northwestern University, Evanston, Il Andreas Matouschek, Ph.D. Host: Devdoot Majumdar, x58427 No 2010-04-29 4 PM 159 Boyer Hall Magda Konarska, Ph.D. TBA Laboratory of Molecular Biology and Biochemistry, The Rockefeller University,New York, NY Magda Konarska, Ph.D. Host: Doug Black, x47644 No 2010-05-06 4 PM 159 Boyer Hall Michael F. Thomashow, Ph.D. TBA Department of Molecular Genetics, MSU-DOE Plant Research Laboratory,Michigan State University, East Lansing Michael F. Thomashow, Ph.D. Host: Chentao Lin, x69576 No 2010-05-20 4 PM 159 Boyer Hall 2010 DAVID S. SIGMAN MEMORAL LECTURE & SYMPOSIUMHonoring 2010 Sigman Lecturer Susan Lindquist, Ph.D. TBA Whitehead Institute for Biomedical Research, Howard Hughes Medical Institute,Broad Institute of MIT and Harvard, Department of Biology, Massachusetts Institute of Technology, Cambridge 2010 DAVID S. SIGMAN MEMORAL LECTURE & SYMPOSIUMHonoring 2010 Sigman Lecturer Susan Lindquist, Ph.D. Host: Carla Koehler, x44834Molecular Biology Institute No 2010-05-27 4 PM 159 Boyer Hall Pao-Tien Chuang, M.D., Ph.D. TBA Department of Biomedical Sciences, Cardiovascular Research Institute,UC San Francisco Pao-Tien Chuang, M.D., Ph.D. Host: Stephen Young, x54934 No